Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14946457 | 0.84 | HSD11B1 (0.51) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL18716599 | 0.84 | HSD11B1 (0.51) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL12313813 | 0.82 | HSD11B1 (0.58) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL21400129 | 0.78 | HSD11B1 (0.56) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL13256444 | 0.77 | RAB9A (0.71) | RAB9ANPC1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL12265806 | 0.74 | HSD11B1 (0.52) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL6667849 | 0.73 | HSD11B1 (0.51) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL17278342 | 0.72 | SMN1; SMN2 (0.70) | RAB9ANPC1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8259816 | 0.72 | MEN1 (0.46) | RAB9ANPC1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL9299468 | 0.72 | RAB9A (0.60) | RAB9ANPC1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | HSD11B1 1012/4885RAB9A 2712/4885NPC1 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.