Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093644 | 0.83 | PDE10A (0.40) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 | |
| SCHEMBL20449121 | 0.76 | KDM1A (0.43) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 | |
| SCHEMBL20449122 | 0.76 | KDM1A (0.43) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 | |
| SCHEMBL9050013 | 0.75 | KDM4E (0.42) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 | |
| SCHEMBL2908444 | 0.74 | PDE10A (0.45) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 | |
| SCHEMBL2910280 | 0.74 | PDE10A (0.45) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 | |
| SCHEMBL90572 | 0.74 | PDE10A (0.45) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 | |
| Hydrochloric Acid SCHEMBL10626673 | 0.72 | GSK3B (0.45) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 | |
| SCHEMBL2708307 | 0.72 | ADRB1 (0.50) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 | |
| SCHEMBL10388908 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4EPDE10AGSK3BRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242278-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI (JP) | 2012-04-26 | — | — | US | disclosed |
| EP-1473286-B1 | PROCESS FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI | 2009-08-27 | — | — | US | disclosed |
| US-7554000-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| CN-1303043-C | Process for producing biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2007-03-07 | — | — | CN | disclosed |
| CN-1642879-A | Process for preparing diaryl compounds | SUMITOMO CHEMICAL CO (JP) | 2005-07-20 | — | — | CN | disclosed |
| US-20050096471-A1 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0527081-B1 | Substituted 3-piperazinylalkyl-2,3-dihydro-4H-1,3-benzoxazine-4-ones, their preparation and their therapeutical use | PF MEDICAMENT (FR) | 1996-01-03 | — | — | EP | disclosed |
| EP-0294307-B1 | 3-Arylcarbamoyl-5-aminomethyl-oxazolidines, and their salts with pharmaceutically acceptable acids | CORTIAL (FR) | 1994-06-22 | — | — | EP | disclosed |
| EP-0527081-A1 | Substituted 3-piperazinylalkyl-2,3-dihydro-4H-1,3-benzoxazine-4-ones, their preparation and their therapeutical use | PIERRE FABRE MEDICAMENT (FR) | 1993-02-10 | — | — | EP | disclosed |
| EP-0294307-A1 | 3-Arylcarbamoyl-5-aminomethyl-oxazolidines, and their salts with pharmaceutically acceptable acids | CORTIAL S.A. (FR) | 1988-12-07 | — | — | EP | disclosed |
| EP-0173634-B1 | 4-(ARYLPIPERAZINYLETHYLAMINOETHOXY) PHENOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL APPLICATION | CORTIAL S.A. (FR) | 1988-08-31 | — | — | EP | disclosed |
| EP-0173634-A1 | 4-(Arylpiperazinylethylaminoethoxy) phenol derivatives, process for their preparation and their therapeutical application | CORTIAL S.A. (FR) | 1986-03-05 | — | — | EP | disclosed |
| EP-0078756-A1 | 2-(4-Phenyl-piperazinylethyl) anilines, process for their preparation and their use in medicine | CORTIAL S.A. (FR) | 1983-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | ALDH1A1 1191/4885KDM4E 3428/4885PDE10A 2773/4885 |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | ALDH1A1 1191/4885KDM4E 3428/4885PDE10A 2773/4885 |
| US-20050096471-A1 | Process for producing biaryl compound | PPOX, CAT, TYR | ALDH1A1 1191/4885KDM4E 3428/4885PDE10A 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.