Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401831 | 0.81 | G6PC1 (0.45) | G6PC1KMT2AMEN1TRPM8ALOX5 | |
| SCHEMBL21392785 | 0.77 | G6PC1 (0.41) | G6PC1KMT2AMEN1TRPM8ALOX5 | |
| SCHEMBL6911592 | 0.74 | ALOX5 (0.44) | G6PC1KMT2AMEN1TRPM8ALOX5 | |
| SCHEMBL14667522 | 0.74 | G6PC1 (0.57) | G6PC1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7373897 | 0.74 | G6PC1 (0.57) | G6PC1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2615559 | 0.74 | G6PC1 (0.57) | G6PC1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6152133 | 0.72 | G6PC1 (0.41) | G6PC1KMT2AMEN1TRPM8ALOX5 | |
| SCHEMBL3091960 | 0.69 | NOS2 (0.60) | ALDH1A1LMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL6901967 | 0.69 | NOS2 (0.60) | ALDH1A1LMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL6901975 | 0.69 | NOS2 (0.60) | ALDH1A1LMNAMAPK1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183600-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-26 | — | — | WO | disclosed |