SCHEMBL6152133

SCHEMBL6152133

CC(=NN(C(=O)CCCCC(=O)N(N=C(C)c1ccccc1)C(C)c1ccccc1)C(C)c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ G6PC1 P35575 1/20 0.41
▸ CYP1A2 P05177 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ TRPM8 Q7Z2W7 1/20 0.39
▸ ALOX5 P09917 2/20 0.39
▸ PPARA Q07869 2/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ LMNA P02545 2/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ POLB P06746 1/20 0.36
▸ MTOR P42345 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ HDAC3 O15379 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ HDAC1 Q13547 1/20 0.35
▸ HDAC7 Q8WUI4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911592 0.80 ALOX5 (0.44) G6PC1HSD17B10TRPM8ALOX5MEN1
SCHEMBL21401699 0.72 G6PC1 (0.46) G6PC1CYP1A2CYP2D6HSD17B10TRPM8
SCHEMBL21401831 0.71 G6PC1 (0.45) G6PC1CYP1A2CYP2D6HSD17B10TRPM8
SCHEMBL4558972 0.68 LMNA (0.47) ALOX5LMNAPOLBALDH1A1
SCHEMBL21392785 0.68 G6PC1 (0.41) G6PC1CYP1A2CYP2D6HSD17B10TRPM8
SCHEMBL4561031 0.66 TP53 (0.54) CYP1A2TRPM8ALOX5LMNAPOLB
SCHEMBL18867910 0.65 LMNA (0.51) TRPM8ALOX5MAPTLMNAMTOR
SCHEMBL4560573 0.65 ALDH1A1 (0.51) TRPM8ALOX5MAPTLMNAMTOR
SCHEMBL16684532 0.64 TRPM8 (0.55) TRPM8ALOX5L3MBTL1LMNATDP1
SCHEMBL4558955 0.64 ALDH1A1 (0.50) TRPM8ALOX5LMNAPOLBMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3150663-B1 ANTI-VIBRATION RUBBER COMPOSITION AND ANTI-VIBRATION RUBBER BRIDGESTONE CORP (JP) 2018-07-18 — — EP disclosed
US-9617404-B2 Rubber composition, conveyor belt rubber composition, conveyor belt, and belt conveyor device BRIDGESTONE CORPORATION (JP) 2017-04-11 — — US disclosed
EP-3150663-A1 ANTI-VIBRATION RUBBER COMPOSITION AND ANTI-VIBRATION RUBBER Bridgestone Corporation (JP) 2017-04-05 — — EP disclosed
US-20160122519-A1 RUBBER COMPOSITION, CONVEYOR BELT RUBBER COMPOSITION, CONVEYOR BELT, AND BELT CONVEYOR DEVICE BRIDGESTONE CORPORATION (JP) 2016-05-05 — — US disclosed
EP-1095972-B1 Rubber composition and tire BRIDGESTONE CORP (JP) 2005-01-26 — — EP disclosed
US-6787595-B1 WEAR RESISTANCE; LOW HEAT BUILDUP; INCORPORATES CARBON BLACK OF SPECIFIC PROPERTIES BRIDGESTONE CORPORATION (JP) 2004-09-07 — — US disclosed
EP-1095972-A1 Rubber composition and tire Bridgestone Corporation (JP) 2001-05-02 — — EP disclosed
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