SCHEMBL2140229

SCHEMBL2140229

COC(=O)c1cc(Cc2ccccc2)cc(C(=O)OC)c1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
HPGD P15428 2/20 0.58
TSHR P16473 1/20 0.57
LOXL2 Q9Y4K0 1/20 0.56
HIF1A Q16665 2/20 0.55
CYP4F2 P78329 2/20 0.54
CYP4A11 Q02928 2/20 0.54
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 1/20 0.52
SLC7A5 Q01650 1/20 0.51
RAB9A P51151 2/20 0.50
NPC1 O15118 1/20 0.50
MGLL Q99685 1/20 0.48
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2659317 0.90 LMNA (0.60) LMNAHPGDTSHRLOXL2HIF1A
SCHEMBL1408485 0.89 CA12 (0.56) LMNAHPGDTSHRLOXL2HIF1A
SCHEMBL2069334 0.88 LOXL2 (0.68) LMNAHPGDTSHRLOXL2HIF1A
SCHEMBL6158387 0.85 TSHR (0.67) LMNAHPGDTSHRLOXL2CYP4F2
SCHEMBL23120562 0.82 ATM (0.53) LMNAHPGDTSHRLOXL2HIF1A
SCHEMBL15366480 0.81 LMNA (0.54) LMNAHPGDTSHRLOXL2HIF1A
SCHEMBL16143289 0.80 HPGD (0.52) LMNAHPGDTSHRLOXL2CA1
SCHEMBL19039710 0.79 GAA (0.53) LMNAHPGDTSHRLOXL2CYP4F2
SCHEMBL14505830 0.79 HPGD (0.63) LMNAHPGDTSHRLOXL2HIF1A
SCHEMBL2142442 0.79 PLA2G10 (0.53) LMNATSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110317230-B Phosphate derivatives and use thereof 上海昇悦医药科技有限公司 2023-11-07 CN disclosed
WO-2019184866-A1 PHOSPHATE DERIVATIVES AND USE THEREOF 朱青 2019-10-03 WO disclosed
US-8147036-B2 Polyfunctional epoxy compound, epoxy resin, cationic photopolymerizable epoxy resin composition, micro structured member, producing method therefor and liquid discharge head CANON KABUSHIKI KAISHA (JP) 2012-04-03 US disclosed
US-20100271428-A1 POLYFUNCTIONAL EPOXY COMPOUND, EPOXY RESIN, CATIONIC PHOTOPOLYMERIZABLE EPOXY RESIN COMPOSITION, MICRO STRUCTURED MEMBER, PRODUCING METHOD THEREFOR AND LIQUID DISCHARGE HEAD CANON KABUSHIKI KAISHA (JP) 2010-10-28 US disclosed
WO-2007148822-A1 POLYFUNCTIONAL EPOXY COMPOUND, EPOXY RESIN, CATIONIC PHOTOPOLYMERIZABLE EPOXY RESIN COMPOSITION, MICRO STRUCTURED MEMBER, PRODUCING METHOD THEREFOR AND LIQUID DISCHARGE HEAD CANON KABUSHIKI KAISHA (JP) 2007-12-27 WO disclosed
EP-1319646-B1 PROCESS FOR PREPARATION OF 3,5-BISALKYLPHENOLS KOWA CO (JP) 2007-04-18 EP disclosed
US-6806395-B2 FOR PRODUCING 3,5- DIISOPROPYLPHENOL OR A SIMILAR COMPOUND, WHICH SERVES AS AN INTERMEDIATE FOR PRODUCING ANTI-INFLAMMATORY AGENTS, PESTICIDES, ETC. KOWA CO., LTD. (JP) 2004-10-19 US disclosed
US-20040044255-A1 Process for preparation of 3,5-bisalkylphenols KOWA CO., LTD. (JP) 2004-03-04 US disclosed
EP-1319646-A1 PROCESS FOR PREPARATION OF 3,5-BISALKYLPHENOLS Kowa Co., Ltd. (JP) 2003-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040044255-A1 Process for preparation of 3,5-bisalkylphenols ACSL3, HACL2, ARL1 LMNA 2714/4885HPGD 4105/4885TSHR 3117/4885
US-20100271428-A1 POLYFUNCTIONAL EPOXY COMPOUND, EPOXY RESIN, CATIONIC PHOTOPOLYMERIZABLE EPOXY RESIN COMPOSITION, MICRO STRUCTURED MEMBER, PRODUCING METHOD THEREFOR AND LIQUID DISCHARGE HEAD RER1, PNN, TIPRL LMNA 2168/4885HPGD 1028/4885TSHR 2759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.