Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 18/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811494 | 1.00 | LDHA (0.55) | LDHARENPPARA | |
| SCHEMBL2137730 | 1.00 | LDHA (0.55) | LDHARENPPARA | |
| SCHEMBL14788425 | 0.90 | PPARG (0.49) | RENPPARA | |
| SCHEMBL14778723 | 0.89 | PPARD (0.53) | LDHARENPPARA | |
| SCHEMBL15184372 | 0.89 | REN (0.55) | REN | |
| SCHEMBL14778721 | 0.89 | REN (0.55) | REN | |
| SCHEMBL14777725 | 0.87 | LDHA (0.49) | LDHARENPPARA | |
| SCHEMBL14777723 | 0.87 | REN (0.53) | REN | |
| SCHEMBL4456020 | 0.86 | REN (0.54) | REN | |
| SCHEMBL4456027 | 0.86 | REN (0.54) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103207247-A | Method of separating and determining aliskiren intermediate and optical isomers thereof by using liquid chromatography | BEIJING WANQUAN DEZHONG MEDICAL BIOLOG TECHNOLOGY CO LTD | 2013-07-17 | — | — | CN | disclosed |
| CN-101120010-B | Metallocene-based phosphorus chiral phosphines | SOLVIAS AG | 2013-07-03 | — | — | CN | disclosed |
| US-7935841-B2 | Bisphospholanes for use as catalysts in asymmetric reactions | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-05-03 | — | — | US | disclosed |
| US-7935841-B2 | Bisphospholanes for use as catalysts in asymmetric reactions | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-05-03 | — | — | US | disclosed |
| US-7906669-B2 | Metallocene-based phosphorus chiral phosphines | SOLVIAS AG (CH) | 2011-03-15 | — | — | US | disclosed |
| EP-1844061-B1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | SOLVIAS AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| US-20090137824-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | PHOENIX CHEMICALS LTD (GB) | 2009-05-28 | — | — | US | disclosed |
| US-20090099358-A1 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | JACKSON PHILIP M | 2009-04-16 | — | — | US | disclosed |
| US-20090099358-A1 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | JACKSON PHILIP M | 2009-04-16 | — | — | US | disclosed |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | PHOENIX CHEMICALS LTD. (GB) | 2008-10-02 | — | — | US | disclosed |
| CN-101133011-A | Process for the manufacture of substituted propionic acids | PHOENIX CHEMICALS LTD (GB) | 2008-02-27 | — | — | CN | disclosed |
| CN-101120010-A | Metallocene-based phosphorus chiral phosphines | PHOENIX CHEMICALS LTD (GB) | 2008-02-06 | — | — | CN | disclosed |
| WO-2007123957-A2 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-11-01 | — | — | WO | disclosed |
| EP-1844061-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | Phoenix Chemicals Limited (GB) | 2007-10-17 | — | — | EP | disclosed |
| EP-1838654-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | Phoenix Chemicals Limited (GB) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006075166-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |
| WO-2006075177-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |
| EP-0678503-B1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | disclosed |
| EP-0678503-A1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099358-A1 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | BPGM, PFKFB3, PFKFB4 | LDHA 870/4885REN 2130/4885PPARA 444/4885 |
| US-20090137824-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | POLL, ZNF207, ZC3HAV1L | LDHA 1376/4885REN 3201/4885PPARA 164/4885 |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | AS3MT, PPA1, AGPS | LDHA 268/4885REN 1227/4885PPARA 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.