SCHEMBL21403595

SCHEMBL21403595

C=CCN(C(=O)OC(C)(C)C)C(C)C(=O)N(C)OC

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
JAK3 P52333 1/20 0.30
BTK Q06187 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22025286 0.82 MEN1 (0.34) FAAHMEN1KMT2A
SCHEMBL21403711 0.81 KMT2A (0.34) FAAHMEN1KMT2A
SCHEMBL21403608 0.81 L3MBTL1 (0.32) MEN1KMT2ADPP4
SCHEMBL10634002 0.81 L3MBTL1 (0.32) MEN1KMT2ADPP4
SCHEMBL6935567 0.81 L3MBTL1 (0.32) MEN1KMT2ADPP4
SCHEMBL21403646 0.80 HDAC6 (0.31) MEN1KMT2ADPP4
SCHEMBL25838348 0.79 MEN1 (0.36) MEN1KMT2ADPP4
SCHEMBL21403728 0.77 SMN1; SMN2 (0.38) MEN1KMT2A
SCHEMBL21403730 0.77 SMN1; SMN2 (0.38) MEN1KMT2A
SCHEMBL19990073 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3774843-B1 DIPEPTIDE PIPERIDINE DERIVATIVES MOLECURE SA (PL) 2022-05-25 EP disclosed
EP-3774843-B1 DIPEPTIDE PIPERIDINE DERIVATIVES MOLECURE SA (PL) 2022-05-25 EP disclosed
US-10851099-B2 Dipeptide piperidine derivatives Oncoarendi Therapeutics S.A. (PL) 2020-12-01 US disclosed
WO-2019186497-A1 DIPEPTIDE PIPERIDINE DERIVATIVES Oncoarendi Therapeutics S.A. (PL) 2019-10-03 WO disclosed
US-20190300525-A1 DIPEPTIDE PIPERIDINE DERIVATIVES Oncoarendi Therapeutics S.A. (PL) 2019-10-03 US disclosed
US-9375497-B2 [F-18]-labeled L-glutamic acid, [F-18]-labeled L-glutamine, derivatives thereof and use thereof and processes for their preparation PIRAMAL IMAGING SA (CH) 2016-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10851099-B2 Dipeptide piperidine derivatives ARG1, ARG2, PEPD FAAH 2284/4885MEN1 4352/4885KMT2A 2932/4885
US-20190300525-A1 DIPEPTIDE PIPERIDINE DERIVATIVES ARG1, ARG2, PEPD FAAH 2284/4885MEN1 4352/4885KMT2A 2932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.