⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033257 | 0.76 | — | — | |
| SCHEMBL28087185 | 0.72 | POLB (0.43) | — | |
| SCHEMBL2124591 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL22468368 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL2124587 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL30509681 | 0.68 | SPR (0.34) | — | |
| SCHEMBL19552510 | 0.68 | — | — | |
| SCHEMBL22719629 | 0.67 | LMNA (0.33) | — | |
| SCHEMBL20590846 | 0.67 | LMNA (0.33) | — | |
| SCHEMBL17491758 | 0.67 | FAAH (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774843-B1 | DIPEPTIDE PIPERIDINE DERIVATIVES | MOLECURE SA (PL) | 2022-05-25 | — | — | EP | disclosed |
| EP-3774843-A1 | DIPEPTIDE PIPERIDINE DERIVATIVES | Oncoarendi Therapeutics SA (PL) | 2021-02-17 | — | — | EP | disclosed |
| US-10851099-B2 | Dipeptide piperidine derivatives | Oncoarendi Therapeutics S.A. (PL) | 2020-12-01 | — | — | US | disclosed |
| WO-2019186497-A1 | DIPEPTIDE PIPERIDINE DERIVATIVES | Oncoarendi Therapeutics S.A. (PL) | 2019-10-03 | — | — | WO | disclosed |
| US-20190300525-A1 | DIPEPTIDE PIPERIDINE DERIVATIVES | Oncoarendi Therapeutics S.A. (PL) | 2019-10-03 | — | — | US | disclosed |