Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21404711 | 1.00 | ACHE (0.60) | ACHETSHRTDP1POLBAPEX1 | |
| SCHEMBL26735492 | 0.98 | ACHE (0.58) | ACHETSHRTDP1POLBAPEX1 | |
| SCHEMBL14998171 | 0.94 | ACHE (0.51) | ACHETSHR | |
| SCHEMBL275243 | 0.94 | TSHR (0.61) | ACHETSHRTDP1POLBAPEX1 | |
| SCHEMBL10057618 | 0.94 | TSHR (0.61) | ACHETSHRTDP1POLBAPEX1 | |
| SCHEMBL21404683 | 0.93 | ACHE (0.56) | ACHETSHRTDP1POLBAPEX1 | |
| SCHEMBL21404659 | 0.93 | ACHE (0.56) | ACHETSHRTDP1POLBAPEX1 | |
| SCHEMBL14368843 | 0.92 | TSHR (0.58) | ACHETSHRTDP1POLBAPEX1 | |
| SCHEMBL24041249 | 0.91 | ACHE (0.51) | ACHETSHRTDP1POLBAPEX1 | |
| SCHEMBL23450390 | 0.89 | TSHR (0.56) | ACHETSHRTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12152045-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | KABUSHIKI KAISHA SHOFU (JP) | 2024-11-26 | — | — | US | disclosed |
| US-20210122770-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2021-04-29 | — | — | US | disclosed |
| US-10975229-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | KABUSHIKI KAISHA SHOFU (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20190300552-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122770-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | SMCHD1, CAD, EPM2A | ACHE 3391/4885TSHR 2902/4885TDP1 2948/4885 |
| US-10975229-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | SMCHD1, CAD, EPM2A | ACHE 3391/4885TSHR 2902/4885TDP1 2948/4885 |
| US-12152045-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | SMCHD1, CAD, EPM2A | ACHE 3391/4885TSHR 2902/4885TDP1 2948/4885 |
| US-20190300552-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | SMCHD1, CAD, EPM2A | ACHE 3391/4885TSHR 2902/4885TDP1 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.