SCHEMBL214054

SCHEMBL214054

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2c1c1ccccc1c1ccccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.67
ALOX12 P18054 2/20 0.67
ALDH1A1 P00352 2/20 0.67
CYP2C9 P11712 1/20 0.67
ALOX15 P16050 1/20 0.67
BRCA1 P38398 1/20 0.67
HSD17B10 Q99714 1/20 0.67
FTO Q9C0B1 8/20 0.59
MAPT P10636 3/20 0.59
MEN1 O00255 2/20 0.59
HTT P42858 2/20 0.59
KMT2A Q03164 2/20 0.59
SMAD3 P84022 2/20 0.59
CYP2C19 P33261 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
PRMT1 Q99873 1/20 0.59
ACE2 Q9BYF1 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
DHFR P00374 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10324292 0.81 HPGD (0.59) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL649476 0.80 DHFR (0.67) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL2557451 0.80 ALDH1A1 (0.64) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL486832 0.80 HPGD (0.64) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL1608876 0.78 HPGD (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL1263259 0.78 HPGD (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL4304748 0.78 HPGD (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL340741 0.78 HPGD (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL30887310 0.78 ALDH1A1 (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL79627 0.78 HPGD (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507603-B1 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE LIFE TECHNOLOGIES CORP (US) 2024-03-06 EP claimed
US-5773236-A FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS MOLECULE PROBES, INC. (US) 1998-06-30 US claimed
US-5516864-A Fluorescent ion-selective diaryldiaza crown ether conjugates MOLECULAR PROBES, INC. (US) 1996-05-14 US claimed
US-5405975-A Detectors for alkali metal ions in aqueous solution MOLECULAR PROBES, INC. (US) 1995-04-11 US claimed
WO-2024130117-A1 SYSTEMS AND METHODS FOR ANALYTE DETECTION Adaptyx Biosciences, Inc. (US) 2024-06-20 WO disclosed
US-20240197213-A1 SYSTEMS AND METHODS FOR ANALYTE DETECTION Adaptyx Biosciences, Inc. 2024-06-20 US disclosed
EP-4373890-A1 DIBENZOXANTHENE QUENCHERS, USES, AND METHODS OF PREPARATION Life Technologies Corporation (US) 2024-05-29 EP disclosed
US-20240167080-A1 METHODS FOR NUCLEIC ACID DETECTION ULTIMA GENOMICS, INC. 2024-05-23 US disclosed
US-20240110063-A1 DIBENZOXANTHENE QUENCHERS, USES, AND METHODS OF PREPARATION Life Technologies Corporation 2024-04-04 US disclosed
EP-3507603-B1 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE LIFE TECHNOLOGIES CORP (US) 2024-03-06 EP disclosed
US-20240042062-A1 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE Life Technologies Corporation (US) 2024-02-08 US disclosed
US-11865191-B2 Compositions and methods for enhanced fluorescence Life Technologies Corporation (US) 2024-01-09 US disclosed
US-6323337-B1 DETECTING AMPLIFICATION OF TARGET NUCLEIC ACID THAT REDUCES FLUORESCENCE; LUMINESCENCE REDUCTION; COVALENTLY BONDING MOLECULAR PROBES, INC. 2001-11-27 US disclosed
EP-1090073-A1 XANTHENE DYES AND THEIR APPLICATION AS LUMINESCENCE QUENCHING COMPOUNDS Molecular Probes Inc. (US) 2001-04-11 EP disclosed
WO-2000064988-A1 XANTHENE DYES AND THEIR APPLICATION AS LUMINESCENCE QUENCHING COMPOUNDS MOLECULAR PROBES, INC. (US) 2000-11-02 WO disclosed
US-5773236-A FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS MOLECULE PROBES, INC. (US) 1998-06-30 US disclosed
US-5773227-A CHELATE COMPOUNDS, FLUORESCENT INDICATOR AND TARGET PEPTIDES MOLECULAR PROBES, INC. (US) 1998-06-30 US disclosed
US-5516864-A Fluorescent ion-selective diaryldiaza crown ether conjugates MOLECULAR PROBES, INC. (US) 1996-05-14 US disclosed
US-5405975-A Detectors for alkali metal ions in aqueous solution MOLECULAR PROBES, INC. (US) 1995-04-11 US disclosed
US-5066580-A Fluorescent dyes coupled to antibodies useful in cell detection, blood, urine, bone marrow analysis BECTON DICKINSON AND COMPANY (US) 1991-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240042062-A1 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE ANXA5, HNRNPF, ANXA6 HPGD 3776/4885ALOX12 2630/4885ALDH1A1 2920/4885
US-11865191-B2 Compositions and methods for enhanced fluorescence ANXA5, HNRNPF, ANXA6 HPGD 3776/4885ALOX12 2630/4885ALDH1A1 2920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.