Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146060 | 0.87 | HPGD (0.50) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL1682613 | 0.86 | FTO (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL1689593 | 0.84 | ALDH1A1 (0.44) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL29361906 | 0.84 | ALDH1A1 (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL273427 | 0.84 | FTO (0.59) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL30887311 | 0.84 | ALDH1A1 (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL134733 | 0.84 | ALDH1A1 (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL30887310 | 0.84 | ALDH1A1 (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL12488503 | 0.83 | HPGD (0.51) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL9474742 | 0.83 | FTO (0.58) | HPGDALDH1A1BRCA1HSD17B10ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 798 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201380-A1 | NON-INVASIVE AND LONGITUDINAL MONITORING OF MICROGLIAL ACTIVATION IN RAT BRAIN WITH SUPERMAGNETIC NANOPARTICLE ENHANCED MR IMAGING | UNM RAINFOREST INNOVATIONS (US) | 2023-06-29 | — | — | US | claimed |
| WO-2021242896-A1 | NON-INVASIVE AND LONGITUDINAL MONITORING OF MICROGLIAL ACTIVATION IN RAT BRAIN WITH SUPERMAGNETIC NANOPARTICLE ENHANCED MR IMAGING | UNM RAINFOREST INNOVATIONS (US) | 2021-12-02 | — | — | WO | claimed |
| US-9939447-B2 | Methods and compositions for analyzing proteins | MONOGRAM BIOSCIENCES, INC. (US) | 2018-04-10 | — | — | US | claimed |
| US-20160069893-A1 | Methods and Compositions for Analyzing Proteins | MONOGRAM BIOSCIENCES, INC. (US) | 2016-03-10 | — | — | US | claimed |
| US-9110075-B2 | Compositions for analyzing proteins | MONOGRAM BIOSCIENCES, INC. (US) | 2015-08-18 | — | — | US | claimed |
| US-8604186-B2 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2013-12-10 | — | — | US | claimed |
| US-20120196295-A1 | UV Excitable Fluorescent Energy Transfer Dyes | Life Technologies Corporation (US) | 2012-08-02 | — | — | US | claimed |
| US-8129529-B2 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2012-03-06 | — | — | US | claimed |
| US-20110077415-A1 | UV Excitable Fluorescent Energy Transfer Dyes | Life Technologies Corporation (US) | 2011-03-31 | — | — | US | claimed |
| JP-4644370-B2 | — | — | 2011-03-02 | — | — | JP | claimed |
| EP-0500779-B1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | PERKIN ELMER CORP (US) | 1999-04-21 | — | — | EP | claimed |
| US-5885778-A | USING THE DYES IN DNA ANALYSIS, DNA SEQUENCE DETERMINATION | THE PERKIN-ELMER CORPORATION (US) | 1999-03-23 | — | — | US | claimed |
| US-5863727-A | AN ACCEPTOR FLUOROPHORE EFFICIENTLY ABSORBS ENERGY EMISSION OF A LINKED DONOR XANTHENE FLUOROPHORE LABELLING A OLIGONUCLEOTIDE PRIMER; REAGENT FOR SEQUENCING NUCLEIC ACIDS | THE PERKIN-ELMER CORPORATION | 1999-01-26 | — | — | US | claimed |
| US-5800996-A | Energy transfer dyes with enchanced fluorescence | THE PERKIN ELMER CORPORATION (US) | 1998-09-01 | — | — | US | claimed |
| EP-0805190-A2 | Energy transfer dyes with enhanced fluorescence | PERKIN-ELMER CORPORATION (US) | 1997-11-05 | — | — | EP | claimed |
| JP-2523423-B2 | — | — | 1996-08-07 | — | — | JP | claimed |
| EP-0500779-A4 | — | — | 1994-02-23 | — | — | EP | claimed |
| US-5188934-A | Long wavelength, narrow emission bandwidth fluorescent dyes; automatic DNA sequencing | APPLIED BIOSYSTEMS, INC. (US) | 1993-02-23 | — | — | US | claimed |
| EP-0500779-A1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | THE PERKIN-ELMER CORPORATION (US) | 1992-09-02 | — | — | EP | claimed |
| WO-1991007507-A1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | APPLIED BIOSYSTEMS, INC. (US) | 1991-05-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196295-A1 | UV Excitable Fluorescent Energy Transfer Dyes | SLC46A1, SLC43A3, SLC25A4 | HPGD 164/4885ALDH1A1 631/4885BRCA1 1486/4885 |
| US-20160069893-A1 | Methods and Compositions for Analyzing Proteins | PTMS, ANPEP, NUDT21 | HPGD 3744/4885ALDH1A1 4389/4885BRCA1 3698/4885 |
| US-20110077415-A1 | UV Excitable Fluorescent Energy Transfer Dyes | SLC46A1, SLC43A3, SLC25A4 | HPGD 164/4885ALDH1A1 631/4885BRCA1 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.