Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.58 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.55 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21424203 | 0.83 | LMNA (0.48) | KMT2APOLBLMNAMAPTALDH1A1 | |
| SCHEMBL21407108 | 0.81 | BMP1 (0.67) | BMP1CAMK2ACAMK2GKMT2ATSHR | |
| SCHEMBL20314689 | 0.78 | ESR1 (0.71) | BMP1CAMK2ACAMK2GTSHRKEAP1 | |
| SCHEMBL21407106 | 0.76 | BMP1 (0.77) | BMP1CAMK2ACAMK2GBACE1KEAP1 | |
| SCHEMBL1631020 | 0.73 | KEAP1 (0.87) | KEAP1NFE2L2 | |
| SCHEMBL21424090 | 0.73 | ALDH1A1 (0.62) | KMT2APOLBLMNAMAPTALDH1A1 | |
| SCHEMBL7004444 | 0.73 | BMP1 (0.71) | BMP1CAMK2ACAMK2GTSHRKEAP1 | |
| SCHEMBL28728523 | 0.72 | CNR1 (0.70) | BMP1CAMK2AKMT2ATSHRMAPK1 | |
| Methane SCHEMBL22905269 | 0.72 | BMP1 (0.60) | BMP1CAMK2ACAMK2GTSHRBACE1 | |
| SCHEMBL7004297 | 0.71 | KEAP1 (0.89) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190300475-A1 | COMPOUNDS TO INHIBIT CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE II AND APPLICATIONS THEREOF | ACADEMIA SINICA (TW) | 2019-10-03 | — | — | US | disclosed |
| US-20190300475-A1 | COMPOUNDS TO INHIBIT CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE II AND APPLICATIONS THEREOF | ACADEMIA SINICA (TW) | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300475-A1 | COMPOUNDS TO INHIBIT CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE II AND APPLICATIONS THEREOF | CAMK2B, CAMK2G, CAMK2A | BMP1 2771/4885CAMK2A 3/4885CAMK2G 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.