SCHEMBL21409705

SCHEMBL21409705

CCCCCCCCC(CCCCCC)C(=O)OC(=O)C(CCCCCC)CCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.55
ZDHHC7 Q9NXF8 1/20 0.52
CA1 P00915 1/20 0.50
GRIK1 P39086 2/20 0.48
GRIK2 Q13002 2/20 0.48
GPR84 Q9NQS5 7/20 0.48
NAAA Q02083 1/20 0.48
FFAR1 O14842 1/20 0.48
MAPT P10636 1/20 0.47
LCK P06239 1/20 0.47
PPARD Q03181 1/20 0.47
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
MAPK1 P28482 1/20 0.45
FAAH O00519 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3075648 1.00 CA2 (0.55) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL27494921 0.98 CA2 (0.59) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL3857579 0.96 CA2 (0.52) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL20370240 0.93 CA2 (0.48) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL27555272 0.92 CA2 (0.63) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL8854677 0.91 CA2 (0.62) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL487325 0.90 GRIK1 (0.54) CA2ZDHHC7GRIK1GRIK2GPR84
SCHEMBL29269937 0.90 CA1 (0.50) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL28610191 0.90 CA1 (0.50) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL28602772 0.90 CA1 (0.50) CA2ZDHHC7CA1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778572-B1 NOVEL CATIONIC LIPID EXHIBITING IMPROVED INTRACELLULAR DYNAMICS NOF CORP (JP) 2025-05-21 EP disclosed
US-20240366508-A1 NOVEL CATIONIC LIPID EXHIBITING IMPROVED INTRACELLULAR DYNAMICS NOF CORPORATION (JP) 2024-11-07 US disclosed
US-12064513-B2 Cationic lipid exhibiting improved intracellular dynamics NOF CORPORATION (JP) 2024-08-20 US disclosed
CN-111902397-B Cationic lipids with improved intracellular kinetics 日油株式会社 2024-04-12 CN disclosed
US-20220192981-A1 CATIONIC LIPID EXHIBITING IMPROVED INTRACELLULAR DYNAMICS NOF CORPORATION (JP) 2022-06-23 US disclosed
EP-3778572-A1 NOVEL CATIONIC LIPID EXHIBITING IMPROVED INTRACELLULAR DYNAMICS NOF Corporation (JP) 2021-02-17 EP disclosed
US-20210023008-A1 NOVEL CATIONIC LIPID EXHIBITING IMPROVED INTRACELLULAR DYNAMICS NOF CORPORATION (JP) 2021-01-28 US disclosed
CN-111902397-A Cationic lipids with improved intracellular kinetics 日油株式会社 2020-11-06 CN disclosed
WO-2019188867-A1 NOVEL CATIONIC LIPID EXHIBITING IMPROVED INTRACELLULAR DYNAMICS 日油株式会社 2019-10-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220192981-A1 CATIONIC LIPID EXHIBITING IMPROVED INTRACELLULAR DYNAMICS ZYX, LIPA, LYPLA1 CA2 2199/4885ZDHHC7 267/4885CA1 3492/4885
US-20210023008-A1 NOVEL CATIONIC LIPID EXHIBITING IMPROVED INTRACELLULAR DYNAMICS ZYX, LIPA, LYPLA1 CA2 2589/4885ZDHHC7 243/4885CA1 3809/4885
US-20240366508-A1 NOVEL CATIONIC LIPID EXHIBITING IMPROVED INTRACELLULAR DYNAMICS ZYX, LIPA, LYPLA1 CA2 2589/4885ZDHHC7 243/4885CA1 3809/4885
US-12064513-B2 Cationic lipid exhibiting improved intracellular dynamics ZYX, LIPA, LYPLA1 CA2 2294/4885ZDHHC7 280/4885CA1 3563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.