SCHEMBL3075648

SCHEMBL3075648

CCCCCCCCCC(CCCCCCC)C(=O)OC(=O)C(CCCCCCC)CCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.55
ZDHHC7 Q9NXF8 1/20 0.52
CA1 P00915 1/20 0.50
GRIK1 P39086 2/20 0.48
GRIK2 Q13002 2/20 0.48
GPR84 Q9NQS5 7/20 0.48
NAAA Q02083 1/20 0.48
FFAR1 O14842 1/20 0.48
MAPT P10636 1/20 0.47
LCK P06239 1/20 0.47
PPARD Q03181 1/20 0.47
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
MAPK1 P28482 1/20 0.45
FAAH O00519 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21409705 1.00 CA2 (0.55) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL27494921 0.98 CA2 (0.59) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL3857579 0.96 CA2 (0.52) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL20370240 0.93 CA2 (0.48) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL27555272 0.92 CA2 (0.63) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL8854677 0.91 CA2 (0.62) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL487325 0.90 GRIK1 (0.54) CA2ZDHHC7GRIK1GRIK2GPR84
SCHEMBL29269937 0.90 CA1 (0.50) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL28610191 0.90 CA1 (0.50) CA2ZDHHC7CA1GRIK1GRIK2
SCHEMBL28602772 0.90 CA1 (0.50) CA2ZDHHC7CA1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3296306-B1 BASE-PROTECTED OLIGONUCLEOTIDE AJINOMOTO KK (JP) 2022-11-09 EP disclosed
EP-2816053-B1 BASE-PROTECTED OLIGONUCLEOTIDE AJINOMOTO KK (JP) 2021-03-24 EP disclosed
CN-106977567-B Oligonucleotide with protected base moiety 味之素株式会社 2021-02-02 CN disclosed
EP-3296306-A1 BASE-PROTECTED OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2018-03-21 EP disclosed
US-9371353-B2 Oligonucleotide with protected base AJINOMOTO CO., INC. (JP) 2016-06-21 US disclosed
US-20150080565-A1 OLIGONUCLEOTIDE WITH PROTECTED BASE AJINOMOTO CO., INC. (JP) 2015-03-19 US disclosed
EP-2816053-A1 BASE-PROTECTED OLIGONUCLEOTIDE Ajinomoto Co., Inc. (JP) 2014-12-24 EP disclosed
US-8846885-B2 Oligonucleotide with protected base AJINOMOTO CO., INC. (JP) 2014-09-30 US disclosed
US-8748358-B2 Lubricating oil additive, lubricating oil composition containing the same, various low-friction sliding members, rolling bearing, and sliding bearing IDEMITSU KOSAN CO., LTD. (JP) 2014-06-10 US disclosed
US-20130267697-A1 OLIGONUCLEOTIDE WITH PROTECTED BASE AJINOMOTO CO., INC. (JP) 2013-10-10 US disclosed
US-20100234254-A1 LUBRICATING OIL ADDITIVE, LUBRICATING OIL COMPOSITION CONTAINING THE SAME, VARIOUS LOW-FRICTION SLIDING MEMBERS, ROLLING BEARING, AND SLIDING BEARING IDEMITSU KOSAN CO., LTD. (JP) 2010-09-16 US disclosed
EP-2011853-A1 LUBRICATING OIL ADDITIVE, LUBRICATING OIL COMPOSITION CONTAINING THE SAME, VARIOUS LOW-FRICTION SLIDING MEMBERS, ROLLING BEARING, AND SLIDING BEARING Idemitsu Kosan Co., Ltd. (JP) 2009-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150080565-A1 OLIGONUCLEOTIDE WITH PROTECTED BASE POLRMT, POLN, RNGTT CA2 3807/4885ZDHHC7 1649/4885CA1 4140/4885
US-20100234254-A1 LUBRICATING OIL ADDITIVE, LUBRICATING OIL COMPOSITION CONTAINING THE SAME, VARIOUS LOW-FRICTION SLIDING MEMBERS, ROLLING BEARING, AND SLIDING BEARING TYK2, TEC, AXL CA2 4417/4885ZDHHC7 1489/4885CA1 3149/4885
US-20130267697-A1 OLIGONUCLEOTIDE WITH PROTECTED BASE POLRMT, POLN, RNGTT CA2 3807/4885ZDHHC7 1649/4885CA1 4140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.