SCHEMBL21409809

SCHEMBL21409809

CCCCO[Si](CCCN)(OCCCC)OCCCC.CO[Si](CCN)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
DNM1 Q05193 8/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
EPHX1 P07099 1/20 0.32
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3623133 0.91 LMNA (0.39) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL202698 0.89 DNM1 (0.40) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL201948 0.87 ADRB2 (0.40) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL691752 0.85 LMNA (0.42) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL4407477 0.84 LMNA (0.44) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL28554977 0.84 LMNA (0.44) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL5816989 0.84 LMNA (0.44) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL28198317 0.83 LMNA (0.39) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL28977725 0.83 LMNA (0.33) LMNA
SCHEMBL201677 0.83 DNM1 (0.44) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019188475-A1 TRIAZINE-RING-CONTAINING POLYMER, RESIN COMPOSITION, CURED FILM, AND SOLID-STATE IMAGING ELEMENT 東レ株式会社 2019-10-03 WO disclosed