Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.49 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21540016 | 1.00 | ALDH1A1 (0.51) | ALDH1A1LMNAALBMAPK1RNASEL | |
| SCHEMBL20325230 | 0.92 | STING1 (0.46) | ALDH1A1LMNAALBMAPK1RNASEL | |
| SCHEMBL21540035 | 0.91 | ALDH1A1 (0.51) | ALDH1A1LMNAALBMAPK1RNASEL | |
| SCHEMBL21539898 | 0.91 | ALDH1A1 (0.51) | ALDH1A1LMNAALBMAPK1RNASEL | |
| SCHEMBL21539867 | 0.91 | ALDH1A1 (0.51) | ALDH1A1LMNAALBMAPK1RNASEL | |
| SCHEMBL22990366 | 0.91 | RNASEL (0.45) | RNASELDTYMK | |
| SCHEMBL20325238 | 0.90 | RNASEL (0.47) | RNASELDNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL21417382 | 0.90 | DTYMK (0.60) | RNASELDNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL21417134 | 0.87 | RNASEL (0.70) | RNASEL | |
| SCHEMBL20324818 | 0.87 | ALDH1A1 (0.50) | ALDH1A1LMNAALBMAPK1RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233882-B1 | FLUORINATED CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | KAYLA THERAPEUTICS (FR) | 2019-10-30 | — | — | EP | disclosed |