SCHEMBL2143446

SCHEMBL2143446

CCCCC(CC)CC1(CC(CC)CCCC)c2ccccc2-c2ccc(-c3nc4cc5oc(-c6ccc7c(c6)C(CC(CC)CCCC)(CC(CC)CCCC)c6ccccc6-7)nc5cc4o3)cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
UTRN P46939 6/20 0.34
CYP1A2 P05177 1/20 0.34
AHR P35869 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
GPR119 Q8TDV5 3/20 0.33
TSHR P16473 2/20 0.32
SNCA P37840 1/20 0.32
NPC1 O15118 4/20 0.32
KDM4E B2RXH2 4/20 0.32
HPGD P15428 3/20 0.32
RAB9A P51151 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 3/20 0.32
HSD17B10 Q99714 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6018363 0.89 MAPT (0.35) MAPTMEN1KMT2AESR1ESR2
SCHEMBL2143267 0.87 RAB9A (0.38) MAPTMEN1KMT2AL3MBTL1ESR1
SCHEMBL13607204 0.83 MEN1 (0.37) MAPTMEN1KMT2AL3MBTL1TSHR
SCHEMBL5502936 0.80 MEN1 (0.38) MAPTMEN1KMT2AL3MBTL1KDM4E
SCHEMBL29377775 0.78 L3MBTL1 (0.46) MAPTMEN1KMT2AL3MBTL1HDAC6
SCHEMBL3721035 0.78 L3MBTL1 (0.46) MAPTMEN1KMT2AL3MBTL1HDAC6
SCHEMBL5503898 0.77 MEN1 (0.35) MAPTMEN1KMT2AL3MBTL1PDK2
SCHEMBL6353229 0.76 MMP12 (0.38) MAPTMEN1KMT2AL3MBTL1CYP1A2
SCHEMBL3159352 0.75 NPC1 (0.38) MAPTMEN1KMT2ACYP1A2TSHR
SCHEMBL6018049 0.75 NPC1 (0.37) MAPTL3MBTL1CYP1A2TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8362275-B2 Dihalogen indolocarbazole monomers and poly(indolocarbazoles) E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-01-29 US disclosed
US-20120241683-A1 Dihalogen Indolocarbazole Monomers and Poly(Indolocarbazoles) LG CHEM, LTD. (KR) 2012-09-27 US disclosed
US-8217181-B2 Dihalogen indolocarbazole monomers and poly (indolocarbazoles) E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-10 US disclosed
US-20110060097-A1 Dihalogen Indolocarbazole Monomers and Poly (Indolocarbazoles) LG CHEM, LTD. (KR) 2011-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110060097-A1 Dihalogen Indolocarbazole Monomers and Poly (Indolocarbazoles) PARG, DDT, MDM4 MAPT 243/4885MEN1 1959/4885KMT2A 1639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.