Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212800 | 0.92 | CNR1 (0.51) | CNR1CNR2 | |
| SCHEMBL14856867 | 0.88 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL214846 | 0.87 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL214048 | 0.87 | CNR1 (0.68) | CNR1CNR2 | |
| SCHEMBL212455 | 0.86 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL4064887 | 0.85 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL212405 | 0.83 | CNR1 (0.61) | CNR1CNR2 | |
| SCHEMBL211895 | 0.81 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL212661 | 0.81 | CNR1 (0.61) | CNR1CNR2 | |
| SCHEMBL14856737 | 0.80 | CNR1 (0.46) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088920-B2 | 3-trifluoromethyl-pyrazine-2-carboxylic acid amide derivatives as HDL-cholesterol raising agents | HOFFMANN-LA ROCHE INC. (US) | 2012-01-03 | — | — | US | claimed |
| US-8088920-B2 | 3-trifluoromethyl-pyrazine-2-carboxylic acid amide derivatives as HDL-cholesterol raising agents | HOFFMANN-LA ROCHE INC. (US) | 2012-01-03 | — | — | US | disclosed |