Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CD81 | P60033 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341491 | 0.81 | CYP2D6 (0.41) | CYP2D6CYP2C19CD81ALDH1A1 | |
| SCHEMBL9571225 | 0.76 | ALDH1A1 (0.35) | CYP2D6CYP2C19CD81ALDH1A1USP2 | |
| SCHEMBL10325237 | 0.75 | FAAH (0.31) | CYP2D6CYP2C19CD81ALDH1A1MAPT | |
| SCHEMBL4919431 | 0.75 | TDP1 (0.35) | TDP1 | |
| SCHEMBL3165539 | 0.73 | ALOX15 (0.34) | CYP2D6CYP2C19CD81ALDH1A1CYP3A4 | |
| SCHEMBL1401881 | 0.73 | CD81 (0.41) | CYP2D6CYP2C19CD81ALDH1A1MAPT | |
| SCHEMBL5008759 | 0.73 | TET2 (0.35) | TDP1 | |
| SCHEMBL1470266 | 0.73 | MEN1 (0.36) | CD81TDP1 | |
| SCHEMBL1470269 | 0.73 | MEN1 (0.36) | CD81TDP1 | |
| SCHEMBL148012 | 0.71 | CD81 (0.40) | CYP2D6CYP2C19CD81ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345686-B1 | Low molecular weight siloxanes with one functional group | GELEST INC (US) | 2018-05-16 | — | — | EP | disclosed |
| EP-1985645-B1 | Low molecular weight siloxanes with one functional group | GELEST INC (US) | 2017-03-15 | — | — | EP | disclosed |
| US-8455599-B2 | Asymmetric low molecular weight siloxanes with one functional group | GELEST TECHNOLOGIES, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| EP-2345686-A2 | Low molecular weight siloxanes with one functional group | GELEST, INC. (US) | 2011-07-20 | — | — | EP | disclosed |
| US-20100298591-A1 | ASYMMETRIC LOW MOLECULAR WEIGHT SILOXANES WITH ONE FUNCTIONAL GROUP | GELEST, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-7799888-B2 | Low molecular weight siloxanes with one functional group | GELEST, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-20080269429-A1 | LOW MOLECULAR WEIGHT SILOXANES WITH ONE FUNCTIONAL GROUP | GELEST, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| EP-1985645-A2 | Low molecular weight siloxanes with one functional group | GELEST, INC. (US) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298591-A1 | ASYMMETRIC LOW MOLECULAR WEIGHT SILOXANES WITH ONE FUNCTIONAL GROUP | ILK, LASP1, PCNA | CYP2D6 4580/4885CYP2C19 4671/4885CD81 3336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.