Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14196487 | 0.98 | LMNA (0.32) | TSHRCASP1LMNAKDM4ENPSR1 | |
| SCHEMBL7068794 | 0.91 | KDM4E (0.40) | TSHRCASP1LMNAKDM4ENPSR1 | |
| SCHEMBL28306475 | 0.91 | KDM4E (0.40) | TSHRCASP1LMNAKDM4ENPSR1 | |
| SCHEMBL5680306 | 0.85 | TSHR (0.38) | TSHRCASP1 | |
| SCHEMBL17053442 | 0.82 | — | — | |
| SCHEMBL990940 | 0.82 | TSHR (0.39) | TSHRCASP1MEN1KMT2A | |
| SCHEMBL991643 | 0.82 | TSHR (0.39) | TSHRCASP1MEN1KMT2A | |
| SCHEMBL7835717 | 0.81 | FAAH (0.41) | LMNANPSR1MAPTKMT2ACYP1A2 | |
| SCHEMBL991642 | 0.79 | TSHR (0.35) | TSHRCASP1MEN1KMT2A | |
| SCHEMBL991855 | 0.79 | TSHR (0.35) | TSHRCASP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271387-B1 | Process for producing 1,3-oxazolidine derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-08-07 | — | — | US | claimed |
| US-5247009-A | Reacted with an imine and an acid halide, tires | NIPPON ZEON CO., LTD. (JP) | 1993-09-21 | — | — | US | claimed |
| US-4677153-A | REACTING WITH AN ACYL HALIDE AND | NIPPON ZEON CO., LTD. (JP) | 1987-06-30 | — | — | US | claimed |
| JP-5255541-A | — | — | None | — | — | JP | disclosed |
| US-20120232107-A1 | NON-PEPTIDE ANTAGONISTS OF GASTRIN RELEASING PEPTIDE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH | 2012-09-13 | — | — | US | disclosed |
| US-8088924-B2 | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-8088924-B2 | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-8088924-B2 | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | TADA YUKIO | 2010-04-01 | — | — | US | disclosed |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | TADA YUKIO | 2010-04-01 | — | — | US | disclosed |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | TADA YUKIO | 2010-04-01 | — | — | US | disclosed |
| EP-1026161-A1 | Process for producing 1,3-oxazolidine derivatives | Daicel Chemical Industries, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-6045703-A | Separation processes | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-04-04 | — | — | US | disclosed |
| WO-1999065873-A1 | SEPARATION OF EPSILON CAPROLACTAM FROM ISOMERS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |
| US-5312849-A | Modified diene polymer, carbon black | NIPPON ZEON CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| JP-H05255541-A | MODIFIED POLYISOPRENE RUBBER COMPOSITION | NIPPON ZEON CO LTD | 1993-10-05 | — | — | JP | disclosed |
| US-5247009-A | Reacted with an imine and an acid halide, tires | NIPPON ZEON CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0198294-B1 | METHOD FOR MODIFYING RUBBERS | NIPPON ZEON CO., LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |
| US-4677153-A | REACTING WITH AN ACYL HALIDE AND | NIPPON ZEON CO., LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0198294-A1 | Method for modifying rubbers | NIPPON ZEON CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232107-A1 | NON-PEPTIDE ANTAGONISTS OF GASTRIN RELEASING PEPTIDE | GRPR, GIPR, CCKBR | TSHR 189/4885CASP1 3444/4885LMNA 4658/4885 |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | CNR2, CNR1, NPY2R | TSHR 185/4885CASP1 3228/4885LMNA 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.