SCHEMBL5680306

SCHEMBL5680306

CCCN=C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
CASP1 P29466 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17053442 0.97
SCHEMBL214406 0.85 TSHR (0.35) TSHRCASP1
SCHEMBL14196487 0.82 LMNA (0.32) TSHRCASP1
SCHEMBL28306475 0.81 KDM4E (0.40) TSHRCASP1
SCHEMBL7068794 0.81 KDM4E (0.40) TSHRCASP1
SCHEMBL8364685 0.78
SCHEMBL991643 0.76 TSHR (0.39) TSHRCASP1
SCHEMBL990940 0.76 TSHR (0.39) TSHRCASP1
SCHEMBL11517546 0.75 HRH3 (0.31) TSHRCASP1
SCHEMBL3974406 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114867778-A Rubber composition and tire 株式会社普利司通 2022-08-05 CN disclosed
CN-110049967-B Novel compound and modified conjugated diene polymer containing functional group derived from the compound 株式会社LG化学 2022-07-12 CN disclosed
CN-110248969-B Method for continuous synthesis of modified diene elastomers using lithium amide initiators 米其林集团总公司 2022-02-25 CN disclosed
CN-108136827-B Rubber composition comprising a diene elastomer having a functional group in the middle of the chain 米其林集团总公司 2020-10-27 CN disclosed
CN-108136828-B Diene elastomer having functional group in the middle of chain and rubber composition containing the same 米其林集团总公司 2020-06-23 CN disclosed
EP-3395822-B1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME VERSUM MAT US LLC (US) 2020-03-25 EP disclosed
CN-110049967-A Novel compound and modified conjugated diene-based polymer containing functional group derived from the compound 株式会社LG化学 2019-07-23 CN disclosed
US-10294250-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2019-05-21 US disclosed
EP-2913334-B1 Organoaminosilanes and methods for making same VERSUM MAT US LLC (US) 2018-12-19 EP disclosed
EP-3395822-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME Versum Materials US, LLC (US) 2018-10-31 EP disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
EP-2913334-A1 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-02 EP disclosed
EP-1451198-B1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES,IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES GEN ELECTRIC (US) 2006-03-01 EP disclosed
US-6998499-B2 Process for the preparation of secondary and tertiary amino-functional silanes, iminoorganosilanes and/or imidoorganosilanes GENERAL ELECTRIC COMPANY (US) 2006-02-14 US disclosed
EP-1451198-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES,IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES GENERAL ELECTRIC COMPANY (US) 2004-09-01 EP disclosed
US-20030220513-A1 Process for the preparation of secondary and tertiary amino-functional silanes, iminoorganosilanes and/or imidoorganosilanes CROMPTON CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2003-11-27 US disclosed
US-6586612-B2 Reacting N-benzylidene aniline with 3-aminopropyltrimethoxy-silane to from N-benzylidene aminopropyltrimethoxysilane used as adhesion promoters in adhesives and sealants or couplers for plastics and glass fibers CROMPTON CORPORATION 2003-07-01 US disclosed
WO-2003044026-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES, IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES GENERAL ELECTRIC COMPANY (US) 2003-05-30 WO disclosed
US-20030097014-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES, IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. 2003-05-22 US disclosed
US-4163024-A NICKEL CATALYST STUDIENGESELLSCHAFT KOHLE MBH. (DE) 1979-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT TSHR 3989/4885CASP1 1160/4885
US-20030097014-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES, IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES INMT, SI, DAO TSHR 2478/4885CASP1 3581/4885
US-10294250-B2 Organoaminosilanes and methods for making same DDAH1, IDUA, DDT TSHR 3989/4885CASP1 1160/4885
US-20030220513-A1 Process for the preparation of secondary and tertiary amino-functional silanes, iminoorganosilanes and/or imidoorganosilanes INMT, SI, DAO TSHR 2478/4885CASP1 3581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.