SCHEMBL2144201

SCHEMBL2144201

C=C(CC(=O)OC)C(=O)O[Si](C(C)(C)C)(C(C)(C)C)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
TET2 Q6N021 1/20 0.34
TSHR P16473 3/20 0.33
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2144683 0.79 MGAM (0.39) MGAMGAASIMGAM2TET2
SCHEMBL74775 0.75 ALDH1A1 (0.48) MGAMGAASIMGAM2TET2
SCHEMBL7223189 0.75 CA2 (0.40) MGAMGAASIMGAM2TET2
SCHEMBL2144033 0.74 MGAM (0.35) MGAMGAASIMGAM2TET2
SCHEMBL2144183 0.74 TSHR (0.38) MGAMGAASIMGAM2TET2
Hydrochloric Acid SCHEMBL10879426 0.73 ALDH1A1 (0.46) MGAMGAASIMGAM2TET2
SCHEMBL27407766 0.73 ALDH1A1 (0.46) MGAMGAASIMGAM2TET2
SCHEMBL5940227 0.73 ALDH1A1 (0.46) TSHRALDH1A1HSD17B10
Fluoride SCHEMBL28064944 0.73 ALDH1A1 (0.46) MGAMGAASIMGAM2TET2
SCHEMBL2144530 0.71 MGAM (0.33) MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed