SCHEMBL2144683

SCHEMBL2144683

C=C(CC(=O)OC)C(=O)O[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
TSHR P16473 4/20 0.37
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TET2 Q6N021 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3295125 0.89 ALDH1A1 (0.31) ALDH1A1
SCHEMBL8642435 0.83 ALDH1A1 (0.39) MGAMGAASIMGAM2TSHR
SCHEMBL2144183 0.82 TSHR (0.38) MGAMGAASIMGAM2TSHR
SCHEMBL27876442 0.81 ALOX15 (0.39) ALDH1A1HSD17B10
SCHEMBL74775 0.80 ALDH1A1 (0.48) MGAMGAASIMGAM2TSHR
SCHEMBL2144201 0.79 MGAM (0.35) MGAMGAASIMGAM2TSHR
SCHEMBL2144033 0.79 MGAM (0.35) MGAMGAASIMGAM2TSHR
SCHEMBL14823522 0.78 MGAM (0.42) MGAMGAASIMGAM2TSHR
SCHEMBL1155483 0.78 TSHR (0.40) GAATSHRALDH1A1HSD17B10
SCHEMBL2144342 0.78 TSHR (0.36) MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
US-6887649-B2 Multi-layered resist structure and manufacturing method of semiconductor device FUJITSU LIMITED (JP) 2005-05-03 US disclosed
US-20020192595-A1 Multi-layered resist structure and manufacturing method of semiconductor device FUJITSU LIMITED (JP) 2002-12-19 US disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed