SCHEMBL2144183

SCHEMBL2144183

C=C(CC(=O)OC)C(=O)O[Si](C)(C)CC

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
ALDH1A1 P00352 2/20 0.31
HSD17B10 Q99714 1/20 0.31
LMNA P02545 1/20 0.31
TET2 Q6N021 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2144342 0.84 TSHR (0.36) TSHRMGAMGAASIMGAM2
SCHEMBL8642439 0.83 ALOX15 (0.35) HSD17B10
SCHEMBL2144683 0.82 MGAM (0.39) TSHRMGAMGAASIMGAM2
SCHEMBL5839559 0.76 ALDH1A1 (0.44) TSHRALDH1A1
SCHEMBL74775 0.75 ALDH1A1 (0.48) TSHRMGAMGAASIMGAM2
SCHEMBL2144201 0.74 MGAM (0.35) TSHRMGAMGAASIMGAM2
SCHEMBL2144033 0.74 MGAM (0.35) TSHRMGAMGAASIMGAM2
Alcohol SCHEMBL6418303 0.74 MGAM (0.42) TSHRMGAMGAASIMGAM2
Butane SCHEMBL14335055 0.74 ALDH1A1 (0.42) TSHRMGAMGAASIMGAM2
Hydrochloric Acid SCHEMBL10879426 0.73 ALDH1A1 (0.46) TSHRMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed