Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11629366 | 0.85 | LNPEP (0.46) | L3MBTL1CYP19A1TDP1 | |
| SCHEMBL487201 | 0.81 | KDM4E (0.56) | SREBF2KDM4ELMNACYP3A4TSHR | |
| SCHEMBL18924413 | 0.79 | MME (0.39) | TSHRHTR2BNR3C2L3MBTL1ALDH1A1 | |
| SCHEMBL2619306 | 0.79 | CYP1A2 (0.47) | SREBF2KDM4ELMNACYP3A4TSHR | |
| SCHEMBL18924479 | 0.79 | ESR1 (0.43) | TSHRHTR2BNR3C2L3MBTL1CALM1 | |
| SCHEMBL13562418 | 0.78 | NOS2 (0.53) | KDM4EHTR2BL3MBTL1CALM1ALDH1A1 | |
| SCHEMBL5115091 | 0.78 | RECQL (0.50) | TSHRHTR2BL3MBTL1CALM1ALDH1A1 | |
| SCHEMBL24923570 | 0.77 | SREBF2 (0.44) | SREBF2KDM4ELMNACYP3A4TSHR | |
| SCHEMBL18937949 | 0.76 | L3MBTL1 (0.61) | KDM4ELMNATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL21686484 | 0.76 | KDM4E (0.41) | SREBF2KDM4ELMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3549934-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2019-10-09 | — | — | EP | disclosed |