SCHEMBL2144485

SCHEMBL2144485

[CH2][Si](c1ccc(O)cc1)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
HSD17B10 Q99714 3/20 0.50
ALOX15 P16050 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
CA3 P07451 3/20 0.50
CA14 Q9ULX7 3/20 0.50
NPC1 O15118 2/20 0.50
NFKB1 P19838 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
HIF1A Q16665 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
CA9 Q16790 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GMNN O75496 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2542879 0.73 ALOX15 (0.57) MAPTHSD17B10ALOX15MEN1KMT2A
Hydroquinone SCHEMBL18095025 0.71 HSD17B10 (0.80) MAPTHSD17B10ALOX15MEN1KMT2A
SCHEMBL15684574 0.71 ALOX15 (0.53) MAPTHSD17B10ALOX15MEN1KMT2A
Hydroquinone SCHEMBL11511669 0.71 ALOX15 (1.00) MAPTHSD17B10ALOX15MEN1KMT2A
Hydroquinone SCHEMBL460669 0.71 ALOX15 (1.00) MAPTHSD17B10ALOX15MEN1KMT2A
Hydroquinone SCHEMBL15516 0.71
SCHEMBL834965 0.69 ESR1 (0.80) MAPTHSD17B10ALOX15MEN1KMT2A
SCHEMBL9165768 0.69 MEN1 (0.50) MAPTHSD17B10ALOX15MEN1KMT2A
SCHEMBL78718 0.69 ESR1 (0.56) MAPTHSD17B10ALOX15MEN1KMT2A
SCHEMBL2144488 0.69 ESR1 (0.56) MAPTHSD17B10ALOX15MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed