SCHEMBL78718

SCHEMBL78718

C[Si](C)(C)c1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.56
ESR2 Q92731 4/20 0.56
CYP3A4 P08684 4/20 0.50
HSD17B10 Q99714 4/20 0.50
ALOX15 P16050 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
LMNA P02545 3/20 0.50
MAPT P10636 3/20 0.50
HIF1A Q16665 3/20 0.50
NPC1 O15118 2/20 0.50
TYR P14679 2/20 0.50
HPGD P15428 2/20 0.50
NFKB1 P19838 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CA3 P07451 2/20 0.50
CA14 Q9ULX7 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CA12 O43570 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13385395 0.92 ESR1 (0.58) ESR1ESR2CYP3A4HSD17B10ALOX15
SCHEMBL586534 0.83 NR1H2 (0.50) ESR1ESR2HPGDNR1H2NR1H3
4-Vinylphenol SCHEMBL20515239 0.82 ALDH1A1 (0.46) ESR1ESR2MAPTALDH1A1KDM4E
SCHEMBL18816092 0.82 APP (0.64) ESR1ESR2CYP3A4HSD17B10ALOX15
SCHEMBL2144488 0.81 ESR1 (0.56) ESR1ESR2CYP3A4HSD17B10ALOX15
SCHEMBL834965 0.81 ESR1 (0.80) ESR1ESR2CYP3A4HSD17B10ALOX15
SCHEMBL18691997 0.79 ESR1 (0.54) ESR1ESR2CYP3A4HSD17B10ALOX15
SCHEMBL14163946 0.77 ESR1 (0.52) ESR1ESR2CYP3A4HSD17B10ALOX15
SCHEMBL11979357 0.75 NR1H2 (0.46) ESR1ESR2HPGDNR1H2NR1H3
SCHEMBL132491 0.75 ESR1 (0.50) ESR1ESR2CYP3A4HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118932605-A Ultrathin ceramic nanofiber membrane for electronic heat management and preparation method thereof 嘉兴富瑞邦新材料科技有限公司 2024-11-12 CN claimed
CN-118301847-A Flame-retardant high-performance epoxy resin copper-clad plate and preparation method thereof 吉林省大顶山寰川新材料有限公司 2024-07-05 CN claimed
CN-118126728-A Composite surfactant and preparation method and application thereof 上海优创化学品有限公司 2024-06-04 CN claimed
CN-117903345-A Catalyst system containing trialkyl silicon-based phenol compound and preparation and application thereof 中国石油化工股份有限公司 2024-04-19 CN claimed
CN-112226082-A Membrane material for communication based on 5G and preparation method thereof 合肥坤擎机械科技有限公司 2021-01-15 CN claimed
EP-0735425-B1 Esterification product of aromatic novolak resin with quinone diazide sulfonyl compound SHIPLEY CO LLC (US) 2003-06-04 EP claimed
EP-0875793-B1 Toner for developing electrostatic images CANON KK (JP) 2001-10-10 EP claimed
US-5972554-A COMPRISING A PHENOL-ALDEHYDE CONDENSATE RESIN, EXHIBIT A GOOD DISPERSIBILITY IN THE BINDER RESIN AND A GOOD CHARGE CONTROL PERFORMANCE CANON KABUSHIKI KAISHA (JP) 1999-10-26 US claimed
EP-0737895-B1 Photoresist with photoactive compound mixtures SHIPLEY CO LLC (US) 1999-09-08 EP claimed
EP-0875793-A2 Toner for developing electrostatic images CANON KABUSHIKI KAISHA (JP) 1998-11-04 EP claimed
US-5723254-A NOVOLAK ESTERIFIED WITH O-NAPHTHOQUINONE DIAZIDE SHIPLEY COMPANY, L.L.C. (US) 1998-03-03 US claimed
US-5589553-A PHOTORESISTS SHIPLEY COMPANY, L.L.C. (US) 1996-12-31 US claimed
EP-0737895-A1 Photoresist with photoactive compound mixtures Shipley Company LLC (US) 1996-10-16 EP claimed
EP-0735425-A2 Esterification product of aromatic novolak resin with quinone diazide sulfonyl compound Shipley Company LLC (US) 1996-10-02 EP claimed
US-5419995-A Photoresist composition with alternating or block copolymer resins and positive-working o-quinone diazide or negative-working azide sensitizer compound SHIPLEY COMPANY INC. (US) 1995-05-30 US claimed
US-5238776-A Improved thermal properties, etch resistance, high speed SHIPLEY COMPANY INC. (US) 1993-08-24 US claimed
US-5130410-A Condencing a bishydroxymethyl phenol with a reactive phenol in the absence of an aldehyde to form an alternating copolymer and reacting in the presence of an aromatic aldehyde SHIPLEY COMPANY INC. (US) 1992-07-14 US claimed
JP-63292129-A None JP disclosed
US-4105648-A CROSSLINKED POLYACRYLAMIDES CONTAINING SILYL GROUPS CIBA-GEIGY CORPORATION (US) 1978-08-08 US disclosed
US-4000265-A SILICON COMPOUNDS SOCIETE CORTIAL (FR) 1976-12-28 US disclosed