Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12749928 | 0.84 | TAS1R3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL20642405 | 0.78 | ALOX5AP (0.32) | — | |
| SCHEMBL20642375 | 0.78 | GLP1R (0.34) | — | |
| SCHEMBL12895995 | 0.76 | NOS3 (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL12749929 | 0.74 | NPC1 (0.31) | — | |
| SCHEMBL12749932 | 0.74 | ALOX5AP (0.35) | — | |
| SCHEMBL18068087 | 0.72 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL21076469 | 0.72 | — | — | |
| SCHEMBL23842580 | 0.71 | NOS3 (0.41) | NOS3NOS1NOS2 | |
| SCHEMBL20169683 | 0.71 | NOS3 (0.32) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195159-A1 | PRODRUGS OF FUSED-BICYCLIC C5aR ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2019-10-10 | — | — | WO | disclosed |