Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12749929 | 0.85 | NPC1 (0.31) | — | |
| SCHEMBL21446969 | 0.78 | NOS3 (0.31) | — | |
| SCHEMBL22185828 | 0.77 | GLP1R (0.32) | GLP1R | |
| SCHEMBL20642405 | 0.77 | ALOX5AP (0.32) | — | |
| SCHEMBL6050425 | 0.75 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL12749928 | 0.74 | TAS1R3 (0.32) | — | |
| SCHEMBL18068022 | 0.74 | GABRA1 (0.35) | — | |
| SCHEMBL18068021 | 0.74 | GABRA1 (0.35) | — | |
| SCHEMBL20285915 | 0.74 | LMNA (0.39) | — | |
| SCHEMBL12749932 | 0.73 | ALOX5AP (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10179782-B2 | Substituted sulfonamide compounds | GENENTECH, INC. (US) | 2019-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179782-B2 | Substituted sulfonamide compounds | TRPA1, TRPV1, TRPV5 | GLP1R 2447/4885MEN1 4664/4885KMT2A 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.