Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 2/20 | 0.41 |
| ▸ | ME1 | P48163 | 2/20 | 0.41 |
| ▸ | ME3 | Q16798 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PARL | Q9H300 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846703 | 0.79 | CYP2C19 (0.36) | CYP2C19HIF1APARLMGLLALOX12 | |
| SCHEMBL15643036 | 0.77 | ADORA3 (0.31) | MGLLPSMB8PSMB5 | |
| SCHEMBL12085975 | 0.77 | TK1 (0.32) | CYP2C19MGLLPSMB8PSMB5 | |
| SCHEMBL10298956 | 0.77 | MEN1 (0.43) | CYP2C19HIF1APSMB8PSMB5ATM | |
| SCHEMBL13708509 | 0.76 | ADORA3 (0.30) | MGLL | |
| SCHEMBL28736686 | 0.75 | KIF11 (0.37) | PARLMGLLALOX12 | |
| SCHEMBL15643035 | 0.75 | KDM4E (0.36) | CYP2C19HIF1APSMB8PSMB5ATM | |
| SCHEMBL2450503 | 0.74 | KMT2A (0.57) | PARLMGLLALOX12KMT2AALDH1A1 | |
| SCHEMBL156185 | 0.74 | KCNN4 (0.50) | ME2ME1ME3CYP2C19HIF1A | |
| SCHEMBL8034045 | 0.74 | CYP2C19 (0.50) | ME2ME1ME3CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195634-A1 | OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO | EPIODYNE, INC. (US) | 2019-10-10 | — | — | WO | disclosed |