SCHEMBL21448040

SCHEMBL21448040

Nc1nc2c(ncn2[C@H]2C[C@@H](OC[PH](=O)O)[C@@H](COP(=O)(O)O[C@@H]3[C@H](F)[C@H](n4cnc5c(N)ncnc54)O[C@@H]3CO)O2)c(=O)[nH]1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 10/20 0.49
▸ DTYMK P23919 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21448249 1.00 RNASEL (0.49) RNASELDTYMK
SCHEMBL21454918 0.95 RNASEL (0.50) RNASEL
SCHEMBL21454924 0.95 RNASEL (0.50) RNASEL
SCHEMBL21448372 0.93 FUT5 (0.48) RNASEL
SCHEMBL21448042 0.93 FUT5 (0.48) RNASEL
SCHEMBL21448250 0.93 FUT5 (0.48) RNASEL
SCHEMBL21516261 0.92 RNASEL (0.58) RNASEL
SCHEMBL21448248 0.91 RNASEL (0.53) RNASEL
SCHEMBL21448257 0.91 RNASEL (0.53) RNASEL
SCHEMBL21511264 0.91 RNASEL (0.53) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019193543-A1 3'3'-CYCLIC DINUCLEOTIDES INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) 2019-10-10 — — WO disclosed
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