SCHEMBL21448042

SCHEMBL21448042

Nc1nc2c(ncn2[C@H]2CC(OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@@H](F)[C@H]3OC[PH](=O)O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FUT5 Q11128 1/20 0.48
▸ F2 P00734 1/20 0.47
▸ RNASEL Q05823 4/20 0.47
▸ STING1 Q86WV6 4/20 0.47
▸ POLB P06746 1/20 0.46
▸ P2RY2 P41231 1/20 0.46
▸ P2RY4 P51582 1/20 0.46
▸ P2RY6 Q15077 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21448250 1.00 FUT5 (0.48) FUT5F2RNASELSTING1POLB
SCHEMBL21448372 1.00 FUT5 (0.48) FUT5F2RNASELSTING1POLB
SCHEMBL21448040 0.93 RNASEL (0.49) RNASEL
SCHEMBL21448249 0.93 RNASEL (0.49) RNASEL
SCHEMBL21511264 0.91 RNASEL (0.53) RNASEL
SCHEMBL21448245 0.91 RNASEL (0.53) RNASEL
SCHEMBL21448254 0.91 RNASEL (0.53) RNASEL
SCHEMBL21448257 0.91 RNASEL (0.53) RNASEL
SCHEMBL21448237 0.91 RNASEL (0.53) RNASEL
SCHEMBL21448248 0.91 RNASEL (0.53) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019193543-A1 3'3'-CYCLIC DINUCLEOTIDES INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) 2019-10-10 — — WO disclosed
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