Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 10/20 | 0.49 |
| ▸ | DTYMK | P23919 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21448040 | 1.00 | RNASEL (0.49) | RNASELDTYMK | |
| SCHEMBL21454918 | 0.95 | RNASEL (0.50) | RNASEL | |
| SCHEMBL21454924 | 0.95 | RNASEL (0.50) | RNASEL | |
| SCHEMBL21448372 | 0.93 | FUT5 (0.48) | RNASEL | |
| SCHEMBL21448042 | 0.93 | FUT5 (0.48) | RNASEL | |
| SCHEMBL21448250 | 0.93 | FUT5 (0.48) | RNASEL | |
| SCHEMBL21516261 | 0.92 | RNASEL (0.58) | RNASEL | |
| SCHEMBL21448248 | 0.91 | RNASEL (0.53) | RNASEL | |
| SCHEMBL21448257 | 0.91 | RNASEL (0.53) | RNASEL | |
| SCHEMBL21511264 | 0.91 | RNASEL (0.53) | RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190322696-A1 | 3'3'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR,V.V.I. (CZ) | 2019-10-24 | — | — | US | disclosed |
| WO-2019193543-A1 | 3'3'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322696-A1 | 3'3'-CYCLIC DINUCLEOTIDES | STING1, CGAS, MAVS | RNASEL 1954/4885DTYMK 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.