Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 4/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11974589 | 0.78 | DPP8 (0.39) | DPP8DPP9DPP7NAMPTMETAP1 | |
| SCHEMBL1782140 | 0.77 | BRD4 (0.46) | CARM1HSD17B3DPP8DPP9DPP7 | |
| SCHEMBL15983781 | 0.77 | HSD17B3 (0.41) | CARM1HSD17B3DPP8DPP9DPP7 | |
| SCHEMBL11974013 | 0.76 | DPP9 (0.44) | DPP8DPP9DPP7NAMPT | |
| Hydrochloric Acid SCHEMBL1026718 | 0.76 | DPP8 (0.38) | DPP8DPP9DPP7NAMPTMETAP1 | |
| Hydrochloric Acid SCHEMBL1028134 | 0.74 | DPP9 (0.43) | DPP8DPP9DPP7NAMPT | |
| SCHEMBL11973938 | 0.73 | MAOA (0.44) | CARM1NAMPT | |
| SCHEMBL11975918 | 0.73 | DRD1 (0.47) | METAP1 | |
| SCHEMBL6125818 | 0.73 | ABHD6 (0.38) | CARM1HSD17B3DPP8DPP9DPP7 | |
| SCHEMBL18782916 | 0.72 | DPP8 (0.43) | CARM1HSD17B3DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344494-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | Signal Pharmaceuticals, LLC (US) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010027500-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2010-03-11 | — | — | WO | disclosed |