Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP9 | Q86TI2 | 11/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.44 |
| ▸ | DPP4 | P27487 | 7/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1028134 | 0.98 | DPP9 (0.43) | DPP9DPP8DPP4DPP7KCNH2 | |
| SCHEMBL11974589 | 0.78 | DPP8 (0.39) | DPP9DPP8DPP4DPP7KCNH2 | |
| SCHEMBL10209346 | 0.77 | DPP9 (0.46) | DPP9DPP8DPP4DPP7KCNH2 | |
| SCHEMBL8228638 | 0.77 | DPP9 (0.47) | DPP9DPP8DPP4DPP7KCNH2 | |
| Hydrochloric Acid SCHEMBL1026718 | 0.76 | DPP8 (0.38) | DPP9DPP8DPP4DPP7KCNH2 | |
| SCHEMBL2145007 | 0.76 | CARM1 (0.42) | DPP9DPP8DPP7NAMPT | |
| SCHEMBL11973938 | 0.73 | MAOA (0.44) | NAMPT | |
| SCHEMBL29824272 | 0.73 | DPP9 (0.56) | DPP9DPP8DPP4DPP7NAMPT | |
| SCHEMBL19675161 | 0.72 | DPP9 (0.47) | DPP9DPP8DPP4DPP7KCNH2 | |
| SCHEMBL19700136 | 0.72 | KCNH2 (0.59) | DPP9DPP8DPP4DPP7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513235-B2 | Homocysteine synthase inhibitor | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| EP-2486925-A1 | THERAPEUTIC AGENT FOR CEREBRAL INFARCTION | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20120196824-A1 | THERAPEUTIC AGENT FOR CEREBRAL INFARCTION | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| WO-2011043479-A1 | THERAPEUTIC AGENT FOR CEREBRAL INFARCTION | 田辺三菱製薬株式会社 (JP) | 2011-04-14 | — | — | WO | disclosed |
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-02-10 | — | — | US | disclosed |
| WO-2009125853-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196824-A1 | THERAPEUTIC AGENT FOR CEREBRAL INFARCTION | FABP7, TIMP3, MMP11 | DPP9 1542/4885DPP8 2320/4885DPP4 1673/4885 |
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | BHMT, CBS, BHMT2 | DPP9 1760/4885DPP8 2916/4885DPP4 3209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.