Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 3/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14364099 | 0.82 | GAA (0.45) | GAAPKMALOX15HSD17B10RAB9A | |
| SCHEMBL206754 | 0.81 | NFKB1 (0.50) | CA1CA2GAAPKMALOX15 | |
| SCHEMBL26991593 | 0.80 | LCK (0.42) | CA1CA2GAAPKMALOX15 | |
| SCHEMBL28834445 | 0.80 | LCK (0.41) | CA1CA2GAAPKMALOX15 | |
| SCHEMBL1504066 | 0.80 | ATR (0.43) | CA1CA2GAAPKMALOX15 | |
| SCHEMBL13983816 | 0.79 | LMNA (0.46) | CA1CA2GAAPKMALOX15 | |
| SCHEMBL380080 | 0.79 | DAO (0.42) | CA1CA2GAAPKMALOX15 | |
| SCHEMBL380561 | 0.78 | L3MBTL1 (0.49) | CA1CA2GAAPKMALOX15 | |
| SCHEMBL15674780 | 0.78 | LMNA (0.42) | CA1CA2GAAPKMALOX15 | |
| SCHEMBL28070546 | 0.78 | CYP17A1 (0.41) | CA1CA2GAAPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019193540-A1 | HETEROARYL DERIVATIVES OF FORMULA (I) AS ATF4 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-10-10 | — | — | WO | disclosed |