Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.49 |
| ▸ | DRD3 | P35462 | 8/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.48 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27219407 | 0.98 | DRD2 (0.48) | DRD2DRD3ABCC9ABCC8KCNJ11 | |
| SCHEMBL5071326 | 0.81 | CYP19A1 (0.43) | — | |
| SCHEMBL21452010 | 0.77 | CYP11B2 (0.50) | KMT2AMCOLN3 | |
| SCHEMBL11060295 | 0.76 | CYP19A1 (0.44) | DRD2DRD3NPSR1KMT2ASIRT2 | |
| SCHEMBL28408881 | 0.76 | HDAC4 (0.42) | — | |
| SCHEMBL28412030 | 0.76 | POLB (0.47) | DRD2DRD3TSHRKMT2ASIRT2 | |
| SCHEMBL26220380 | 0.76 | KDM4E (0.47) | TSHRKMT2A | |
| SCHEMBL1138365 | 0.76 | KDM4E (0.47) | TSHRKMT2A | |
| SCHEMBL5556432 | 0.76 | LMNA (0.46) | TSHRNPSR1 | |
| SCHEMBL6435720 | 0.76 | CYP19A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158340-A1 | PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2024-05-16 | — | — | US | disclosed |
| WO-2022235875-A1 | PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SαAME | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-11-10 | — | — | WO | disclosed |
| US-20210171487-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI JIANHE PHARMACEUTICAL & TECHNOLOGY CO. LTD. (CN) | 2021-06-10 | — | — | US | disclosed |
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019192602-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海键合医药科技有限公司 | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158340-A1 | PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME | AHR, CBR3, AADAC | DRD2 2061/4885DRD3 1842/4885ABCC9 3553/4885 |
| US-20210171487-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, PAH, COMT | DRD2 2133/4885DRD3 2327/4885ABCC9 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.