Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18490302 | 0.78 | OPRD1 (0.44) | NPC1RAB9AL3MBTL1ALDH1A1PTPN2 | |
| SCHEMBL18490289 | 0.70 | TBXAS1 (0.41) | ALDH1A1PTPN2LMNAMEN1KMT2A | |
| SCHEMBL26622018 | 0.69 | PTPN2 (0.47) | NPC1RAB9AL3MBTL1ALDH1A1PTPN2 | |
| SCHEMBL31550045 | 0.68 | PTPN2 (0.43) | NPC1RAB9AL3MBTL1ALDH1A1PTPN2 | |
| SCHEMBL3484110 | 0.67 | STING1 (0.42) | ALDH1A1CSNK1DGSK3AGSK3BDYRK1A | |
| SCHEMBL9431415 | 0.66 | RPS6KB1 (0.44) | NPC1RAB9AL3MBTL1ALDH1A1PTPN2 | |
| SCHEMBL829006 | 0.66 | CSNK2A2 (0.46) | NPC1RAB9AALDH1A1PTPN2RPS6KB1 | |
| SCHEMBL21406179 | 0.65 | STING1 (0.49) | NPC1RAB9A | |
| SCHEMBL26108710 | 0.63 | MTNR1A (0.53) | L3MBTL1ALDH1A1LMNAMTNR1AMTNR1B | |
| SCHEMBL8017091 | 0.62 | CYP3A4 (0.55) | RAB9AL3MBTL1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195124-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |