Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214650 | 0.85 | SLC9A1 (0.41) | TDP1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL23765145 | 0.80 | — | — | |
| SCHEMBL29760312 | 0.78 | TYMS (0.42) | TDP1TP53TYMSALDH1A1MEN1 | |
| SCHEMBL2443320 | 0.78 | TYMS (0.42) | TDP1TP53TYMSALDH1A1MEN1 | |
| SCHEMBL1778036 | 0.78 | ALDH1A1 (0.56) | TDP1TP53TYMSALDH1A1MEN1 | |
| SCHEMBL38666753 | 0.78 | ALDH1A1 (0.56) | TDP1TP53TYMSALDH1A1MEN1 | |
| SCHEMBL216923 | 0.77 | TDP1 (0.39) | TDP1TP53TYMSALDH1A1MEN1 | |
| SCHEMBL215676 | 0.77 | CYP2A6 (0.48) | TDP1TP53TYMSALDH1A1MEN1 | |
| SCHEMBL21244259 | 0.77 | CYP1A2 (0.57) | TDP1TP53TYMSALDH1A1MEN1 | |
| SCHEMBL11963906 | 0.77 | CTDSP1 (0.53) | TDP1TP53TYMSALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110225911-A | Oxadiazolone transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2019-09-10 | — | — | CN | disclosed |
| EP-1780600-B1 | LOWER LAYER FILM FORMING COMPOSITION FOR LITHOGRAPHY INCLUDING NAPHTHALENE RING HAVING HALOGEN ATOM | NISSAN CHEMICAL IND LTD (JP) | 2014-02-26 | — | — | EP | disclosed |
| US-8088546-B2 | Underlayer coating forming composition for lithography containing naphthalene ring having halogen atom | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| EP-2331552-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2011-06-15 | — | — | EP | disclosed |
| CN-1977220-B | Lower layer film forming composition for lithography including naphthalene ring having halogen atom | NISSAN CHEMICAL IND LTD | 2010-12-01 | — | — | CN | disclosed |
| WO-2010036551-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-01 | — | — | WO | disclosed |
| US-20070238029-A1 | Underlayer Coating Forming Composition for Lithography Containing Naphthalene Ring Having Halogen Atom | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1780600-A1 | LOWER LAYER FILM FORMING COMPOSITION FOR LITHOGRAPHY INCLUDING NAPHTHALENE RING HAVING HALOGEN ATOM | Nissan Chemical Industries, Ltd. (JP) | 2007-05-02 | — | — | EP | disclosed |