Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24200212 | 0.84 | ALDH1A1 (0.40) | L3MBTL1PKMALDH1A1HTTLMNA | |
| SCHEMBL21455427 | 0.83 | TBXAS1 (0.42) | TBXAS1L3MBTL1PKMUSP2ALDH1A1 | |
| SCHEMBL21455691 | 0.78 | TBXAS1 (0.42) | TBXAS1L3MBTL1PKMUSP2ALDH1A1 | |
| SCHEMBL24199914 | 0.76 | TBXAS1 (0.39) | TBXAS1L3MBTL1PKMUSP2ALDH1A1 | |
| SCHEMBL21455539 | 0.73 | TBXAS1 (0.36) | TBXAS1L3MBTL1PKMALDH1A1MAPT | |
| SCHEMBL21455800 | 0.73 | TBXAS1 (0.35) | TBXAS1L3MBTL1PKMCYP4F2CYP4A11 | |
| SCHEMBL24200170 | 0.73 | TBXAS1 (0.42) | TBXAS1L3MBTL1PKMUSP2ALDH1A1 | |
| SCHEMBL24200089 | 0.72 | TBXAS1 (0.42) | TBXAS1L3MBTL1PKMUSP2ALDH1A1 | |
| SCHEMBL24200223 | 0.72 | TBXAS1 (0.40) | TBXAS1L3MBTL1PKMUSP2ALDH1A1 | |
| SCHEMBL25899417 | 0.72 | TBXAS1 (0.40) | TBXAS1L3MBTL1PKMUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |