Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455427 | 0.80 | TBXAS1 (0.42) | TBXAS1PKML3MBTL1ALDH1A1 | |
| SCHEMBL24199904 | 0.75 | TBXAS1 (0.43) | TBXAS1PKMHPGDGAAL3MBTL1 | |
| SCHEMBL21455691 | 0.74 | TBXAS1 (0.42) | TBXAS1PKML3MBTL1ALDH1A1 | |
| SCHEMBL21455716 | 0.73 | TBXAS1 (0.37) | TBXAS1PKMHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL21455759 | 0.71 | L3MBTL1 (0.40) | TBXAS1PKMHPGDKDM4EL3MBTL1 | |
| SCHEMBL23616962 | 0.71 | TBXAS1 (0.46) | TBXAS1PKMKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL23425588 | 0.70 | TBXAS1 (0.47) | TBXAS1PKMHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL23241478 | 0.70 | TBXAS1 (0.47) | TBXAS1PKMHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL7888801 | 0.70 | TBXAS1 (0.49) | TBXAS1PKMKDM4EGAAL3MBTL1 | |
| SCHEMBL24200170 | 0.69 | TBXAS1 (0.42) | TBXAS1PKMHPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |