Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455434 | 0.84 | AGBL2 (0.41) | AGBL2CXCL8RXRATSHRCAMK2A | |
| SCHEMBL23261419 | 0.83 | SRC (0.51) | RXRARXRBRXRGTSHRCAMK2A | |
| SCHEMBL21455802 | 0.82 | ALDH1A1 (0.42) | TSHRPKM | |
| SCHEMBL14125958 | 0.82 | HSD17B10 (0.54) | AGBL2CXCL8TSHRCAMK2AHSD17B10 | |
| SCHEMBL29530799 | 0.82 | HSD17B10 (0.54) | AGBL2CXCL8TSHRCAMK2AHSD17B10 | |
| SCHEMBL8418212 | 0.82 | KCNH2 (0.38) | TSHRP2RX3IRAK4 | |
| SCHEMBL20818300 | 0.80 | KCNH2 (0.37) | P2RX3IRAK4 | |
| SCHEMBL3941649 | 0.80 | CXCL8 (0.54) | CXCL8TSHRCAMK2AFFAR4IRAK4 | |
| SCHEMBL28573110 | 0.78 | CSNK2A1 (0.38) | P2RX3 | |
| SCHEMBL21455770 | 0.78 | PTGDR2 (0.40) | RXRARXRBRXRGPTGDR2CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |