SCHEMBL21456895

SCHEMBL21456895

Cc1c(CO)ccc(CO)c1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 2/20 0.37
CD274 Q9NZQ7 2/20 0.37
METAP2 P50579 1/20 0.36
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FABP3 P05413 1/20 0.34
FABP4 P15090 1/20 0.34
FABP5 Q01469 1/20 0.34
PSEN1 P49768 4/20 0.31
PSEN2 P49810 4/20 0.31
APH1B Q8WW43 4/20 0.31
NCSTN Q92542 4/20 0.31
APH1A Q96BI3 4/20 0.31
PSENEN Q9NZ42 4/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1805000 0.86 MEN1 (0.35) PDCD1CD274METAP2KDM4EPOLB
SCHEMBL1804331 0.82 ALDH1A1 (0.40) KDM4EFABP3FABP4FABP5ALDH1A1
SCHEMBL1806098 0.76 PDCD1 (0.39) PDCD1CD274KDM4EPOLBAPEX1
SCHEMBL1804650 0.74 CA2 (0.34) MEN1ALDH1A1LMNAHPGDKMT2A
SCHEMBL13199168 0.74 PDCD1 (0.50) PDCD1CD274METAP2KDM4EMEN1
SCHEMBL8025358 0.73 FABP4 (0.33) METAP2KDM4EPOLBAPEX1TDP1
SCHEMBL1804997 0.72 MEN1 (0.36) KDM4EPOLBAPEX1TDP1FABP3
SCHEMBL1806998 0.72 PDCD1 (0.47) PDCD1CD274APEX1FABP4MEN1
SCHEMBL1803798 0.72 MEN1 (0.33) FABP3FABP4FABP5MEN1KMT2A
SCHEMBL8773054 0.71 CYP2D6 (0.45) KDM4ETDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553103-B1 AQUEOUS URETHANE RESIN COMPOSITION AND SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2025-02-19 EP disclosed
EP-3666970-B1 SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2024-10-09 EP disclosed
US-11795267-B2 Aqueous urethane resin composition and synthetic leather DIC CORPORATION (JP) 2023-10-24 US disclosed
CN-111201347-B Synthetic leather DIC株式会社 2023-03-10 CN disclosed
US-11505896-B2 Synthetic leather DIC CORPORATION (JP) 2022-11-22 US disclosed
CN-109937219-B Aqueous polyurethane resin composition and synthetic leather DIC株式会社 2022-06-28 CN disclosed
US-20200263352-A1 SYNTHETIC LEATHER DIC CORPORATION (JP) 2020-08-20 US disclosed
EP-3666970-A1 SYNTHETIC LEATHER DIC Corporation (JP) 2020-06-17 EP disclosed
CN-111201347-A Synthetic leather DIC株式会社 2020-05-26 CN disclosed
US-20200071452-A1 AQUEOUS URETHANE RESIN COMPOSITION AND SYNTHETIC LEATHER DIC CORPORATION (JP) 2020-03-05 US disclosed
EP-3553103-A1 AQUEOUS URETHANE RESIN COMPOSITION AND SYNTHETIC LEATHER DIC Corporation (JP) 2019-10-16 EP disclosed
CN-109937219-A Aqueous urethane resin composition and synthetic leather DIC株式会社 2019-06-25 CN disclosed