SCHEMBL21457559

SCHEMBL21457559

CC(C)OC(=O)/C(C#N)=C/c1ccc(N(C)C)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDE P14735 2/20 0.69
RAB9A P51151 1/20 0.65
ALDH1A1 P00352 7/20 0.58
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
MAPT P10636 4/20 0.58
PSMD14 O00487 1/20 0.54
PTP4A3 O75365 1/20 0.50
PTP4A2 Q12974 1/20 0.50
PTP4A1 Q93096 1/20 0.50
APP P05067 1/20 0.50
USP2 O75604 1/20 0.50
RECQL P46063 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457562 1.00 IDE (0.69) IDERAB9AALDH1A1MEN1KMT2A
SCHEMBL21457384 0.85 MEN1 (0.66) IDERAB9AALDH1A1MEN1KMT2A
SCHEMBL21457382 0.85 MEN1 (0.66) IDERAB9AALDH1A1MEN1KMT2A
SCHEMBL14701210 0.85 IDE (0.61) IDERAB9AALDH1A1MEN1KMT2A
SCHEMBL21457523 0.84 ALDH1A1 (0.59) IDERAB9AALDH1A1MEN1KMT2A
SCHEMBL21457576 0.84 ALDH1A1 (0.61) IDERAB9AALDH1A1MEN1KMT2A
SCHEMBL21457489 0.84 APP (0.67) IDERAB9AALDH1A1MEN1KMT2A
SCHEMBL21457594 0.84 ALDH1A1 (0.61) IDERAB9AALDH1A1MEN1KMT2A
SCHEMBL21457572 0.84 ALDH1A1 (0.61) IDERAB9AALDH1A1MEN1KMT2A
SCHEMBL21457591 0.84 ALDH1A1 (0.61) IDERAB9AALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
CN-110248971-A Copolymer and the optical film for using the copolymer 东曹株式会社 2019-09-17 CN disclosed