SCHEMBL14701210

SCHEMBL14701210

CC(COC(=O)/C(C#N)=C/c1ccc(N(C)C)cc1)OC(=O)/C(C#N)=C/c1ccc(N(C)C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDE P14735 2/20 0.61
RAB9A P51151 1/20 0.58
MEN1 O00255 7/20 0.54
KMT2A Q03164 7/20 0.54
ALDH1A1 P00352 7/20 0.54
PSMD14 O00487 1/20 0.54
MAPT P10636 5/20 0.51
PPARG P37231 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
NCOR2 Q9Y618 1/20 0.49
USP2 O75604 1/20 0.47
RECQL P46063 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
APP P05067 1/20 0.45
DNM1 Q05193 1/20 0.43
CA12 O43570 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457110 0.91 IDE (0.58) IDERAB9AMEN1KMT2AALDH1A1
SCHEMBL21457112 0.91 IDE (0.58) IDERAB9AMEN1KMT2AALDH1A1
SCHEMBL14701163 0.88 ALDH1A1 (0.59) IDERAB9AMEN1KMT2AALDH1A1
SCHEMBL14701183 0.87 IDE (0.58) IDERAB9AMEN1KMT2AALDH1A1
SCHEMBL14703462 0.87 IDE (0.48) IDERAB9AMEN1KMT2AALDH1A1
SCHEMBL14701178 0.86 ALDH1A1 (0.48) IDERAB9AMEN1KMT2AALDH1A1
SCHEMBL16843403 0.86 IDE (0.55) IDERAB9AMEN1KMT2AALDH1A1
SCHEMBL14701170 0.85 ALDH1A1 (0.56) IDERAB9AMEN1KMT2AALDH1A1
SCHEMBL21457562 0.85 IDE (0.69) IDERAB9AMEN1KMT2AALDH1A1
SCHEMBL21457559 0.85 IDE (0.69) IDERAB9AMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 IDE 3612/4885RAB9A 755/4885MEN1 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.