Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17923119 | 0.80 | ALDH1A1 (0.51) | MAPK1GAAALDH1A1L3MBTL1NOS3 | |
| SCHEMBL23837624 | 0.80 | NOS3 (0.49) | MAPK1GAAALDH1A1L3MBTL1NOS3 | |
| SCHEMBL26686103 | 0.76 | HTT (0.39) | USP30GAAALDH1A1NOS2HTT | |
| SCHEMBL11193856 | 0.76 | CYP2C19 (0.54) | MAPK1GAAALDH1A1L3MBTL1NOS3 | |
| SCHEMBL17700712 | 0.76 | MAPK1 (0.48) | MAPK1GAAALDH1A1L3MBTL1NOS3 | |
| SCHEMBL1443173 | 0.76 | MAPK1 (0.51) | MAPK1USP30GAAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL14744005 | 0.74 | ALDH1A1 (0.52) | MAPK1GAAALDH1A1L3MBTL1NOS3 | |
| SCHEMBL9216393 | 0.73 | HTT (0.50) | GAAALDH1A1L3MBTL1HTTTHRB | |
| SCHEMBL11465551 | 0.72 | ALDH1A1 (0.42) | MAPK1GAAALDH1A1L3MBTL1NOS3 | |
| SCHEMBL3809824 | 0.71 | IL1B (0.47) | MAPK1GAAALDH1A1L3MBTL1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062710-A1 | Method For Producing 3-(Pyridyl-2-Amino)Propionitrile And Analogues Thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2020-02-27 | — | — | US | disclosed |
| EP-3553051-A1 | METHOD FOR PRODUCING 3-(PYRIDYL-2-AMINO)PROPIONITRILE AND ANALOGUES THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2019-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062710-A1 | Method For Producing 3-(Pyridyl-2-Amino)Propionitrile And Analogues Thereof | PDXK, PAH, PNPO | MAPK1 1991/4885USP30 3283/4885GAA 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.