Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.45 |
| ▸ | LAP3 | P28838 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15299885 | 0.84 | MEN1 (0.47) | PSMB1RENPSMB5 | |
| SCHEMBL17596479 | 0.84 | LAP3 (0.50) | PSMB1RENLAP3ANPEPRNPEP | |
| SCHEMBL28027550 | 0.83 | REN (0.40) | PSMB1RENPSMB5MMELTA4H | |
| Hydrochloric Acid SCHEMBL17596560 | 0.83 | LAP3 (0.49) | PSMB1RENLAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL20474482 | 0.83 | LAP3 (0.49) | PSMB1RENLAP3ANPEPRNPEP | |
| SCHEMBL21457977 | 0.82 | CAPN1 (0.50) | MMELTA4H | |
| SCHEMBL20474451 | 0.81 | PSMB1 (0.52) | PSMB1RENPSMB5ANPEPMME | |
| SCHEMBL20474450 | 0.81 | PSMB1 (0.52) | PSMB1RENPSMB5ANPEPMME | |
| SCHEMBL3859084 | 0.81 | PSMB1 (0.52) | PSMB1RENPSMB5ANPEPMME | |
| SCHEMBL17595915 | 0.78 | LAP3 (0.46) | LAP3ANPEPRNPEPDNPEPMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |
| EP-1692098-A1 | ALPHA-KETOAMIDE DERIVATIVE, AND PRODUCTION METHOD AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056519-A1 | ALPHA-KETOAMIDE DERIVATIVE, AND PRODUCTION METHOD AND USE THEREOF | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-06-23 | — | — | WO | disclosed |