Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11424799 | 0.83 | CYP2C19 (0.37) | CYP2C19CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10973208 | 0.78 | CYSLTR2 (0.40) | HTR2A | |
| SCHEMBL4200755 | 0.77 | SMN1; SMN2 (0.42) | CYP2C19CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9301725 | 0.76 | CYP1A2 (0.35) | CYP2C19CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9153275 | 0.76 | RIPK1 (0.33) | CYP2C19CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9067800 | 0.76 | CYP2C19 (0.37) | CYP2C19CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7959062 | 0.75 | SLC6A3 (0.63) | CYP2C19CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL776296 | 0.74 | CYP2C19 (0.36) | CYP2C19CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL776368 | 0.74 | CYP2C19 (0.36) | CYP2C19CYP3A4CYP2D6TSHRKDM4E | |
| SCHEMBL11520655 | 0.74 | LMNA (0.42) | CYP2C19KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521752-B1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW CORNING (US) | 2017-10-25 | — | — | EP | disclosed |
| US-9493615-B2 | Organopolysiloxanes containing an unsaturated group | DOW CORNING CORPORATION (US) | 2016-11-15 | — | — | US | disclosed |
| EP-2521742-A1 | POLYOLEFINS MODIFIED BY SILICONES | Dow Corning Corporation (US) | 2012-11-14 | — | — | EP | disclosed |
| EP-2521752-A1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | Dow Corning Corporation (US) | 2012-11-14 | — | — | EP | disclosed |
| US-20120283362-A1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW SILICONES CORPORATION | 2012-11-08 | — | — | US | disclosed |
| US-20120283388-A1 | POLYOLEFINS MODIFIED BY SILICONES | DOW CORNING EUROPE SA (BE) | 2012-11-08 | — | — | US | disclosed |
| WO-2011083043-A1 | POLYOLEFINS MODIFIED BY SILICONES | DOW CORNING CORPORATION (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011083044-A1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW CORNING CORPORATION (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011083049-A1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW CORNING CORPORATION (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011083048-A1 | DIENE ELASTOMERS MODIFIED BY SILICONES | DOW CORNING CORPORATION (US) | 2011-07-14 | — | — | WO | disclosed |