SCHEMBL9301725

SCHEMBL9301725

C=CC(OCCSC(C=C)c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
SLC6A4 P31645 1/20 0.35
CYP2C19 P33261 1/20 0.35
SLC6A3 Q01959 1/20 0.35
CASR P41180 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193388 0.76 CASR (0.36) CYP1A2CYP3A4CYP2D6TSHRSLC6A4
SCHEMBL9193909 0.76 CASR (0.36) CYP1A2CYP3A4CYP2D6TSHRSLC6A4
SCHEMBL2146152 0.76 CYP2C19 (0.37) CYP1A2CYP3A4CYP2D6CYP2C9TSHR
SCHEMBL874969 0.75 CASR (0.41) CYP1A2CYP2D6TSHRSLC6A4CYP2C19
SCHEMBL11424799 0.75 CYP2C19 (0.37) CYP1A2CYP3A4CYP2D6CYP2C9TSHR
SCHEMBL7778374 0.72 CASR (0.37) CYP1A2CYP2D6TSHRSLC6A4CYP2C19
SCHEMBL28358211 0.72 THRB (0.46)
SCHEMBL8758485 0.72 CASR (0.34) CYP1A2CYP3A4CYP2D6TSHRSLC6A4
SCHEMBL6540266 0.72 LTA4H (0.41) CYP1A2CYP2D6CYP2C9TSHRSLC6A4
SCHEMBL10808238 0.71 CASR (0.34) CYP1A2CYP3A4CYP2D6CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6065190-A None JP disclosed
JP-H0665190-A VINYLBENZYL COMPOUND TOKUYAMA SODA CO LTD 1994-03-08 JP disclosed