SCHEMBL21461879

SCHEMBL21461879

c1ccc(-c2ccc(-c3cc4c5ccccc5c5cccc6c5c4c4c3c3ccccc3n64)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.37
RET P07949 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
PLEC Q15149 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPK14 Q16539 1/20 0.30
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21473097 0.86 HSD17B10 (0.34) HSD17B10KDM4EMEN1MAPTRECQL
SCHEMBL21473078 0.82 HSD17B10 (0.36) HSD17B10KDM4EMEN1MAPTRECQL
SCHEMBL24601589 0.79 HSD17B10 (0.36) HSD17B10RETKDM4EMEN1MAPT
SCHEMBL21472981 0.78 TSPO (0.38) HSD17B10KDM4EMEN1MAPTKMT2A
SCHEMBL21472980 0.78 TSPO (0.38) HSD17B10KDM4EMEN1MAPTKMT2A
SCHEMBL23776039 0.78 HSD17B10 (0.44) HSD17B10RETKDM4EMEN1MAPT
SCHEMBL22178509 0.77 TSPO (0.41) MEN1KMT2A
SCHEMBL22178597 0.77 MAOB (0.41) HSD17B10KDM4EHTR6
SCHEMBL22178499 0.77 TSPO (0.43) HSD17B10HTR6
SCHEMBL22178510 0.77 TSPO (0.43) HSD17B10HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12522608-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2026-01-13 US disclosed
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 HSD17B10 804/4885RET 4154/4885KDM4E 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.